日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

An inactivated trivalent virion-based vaccine protects against aerosol challenge with encephalitic alphaviruses in mice and macaques

一种基于灭活三价病毒颗粒的疫苗可保护小鼠和猕猴免受脑炎甲病毒气溶胶攻击。

Lam, L K Metthew; Gilliland, Theron Jr; Dunn, Matthew; Alcorn-Burckhardt, Maria D; Terada, Yutaka; Sun, Chengqun; Vasilatos, Shauna; Midgett, Morgan; Williams, Connor; Laughlin, Amanda; Lundy, Jeneveve; Gardner, Christina L; Thomas, Archana; Raué, Hans-Peter; Gertje, Hans P; O'Connell, Aoife K; Crossland, Nicholas A; Reed, Douglas S; Diamond, Michael S; Slifka, Mark K; Klimstra, William B

Human-induced Pluripotent Stem Cell-derived Gut Organoids Recapitulate Regional Specific Genetic Programs and a Role for cAMP in Lineage Specification

人诱导多能干细胞来源的肠道类器官重现了区域特异性遗传程序,并揭示了 cAMP 在谱系分化中的作用。

Flores, Elizabeth Y; Mithal, Aditya; Bawa, Pushpinder; Wang, Feiya; D'Amico, Andrew; O'Connell, Aoife K; Gertje, Hans P; Tseng, Anna E; Crossland, Nicholas A; Alekseyev, Yuriy; Mostoslavsky, Gustavo

Dysplastic lung repair fosters a tuberculosis-promoting microenvironment through maladaptive macrophage polarization

发育不良的肺修复通过巨噬细胞极化异常促进结核病的微环境。

Shivraj M Yabaji ,Suruchi Lata ,Anna E Tseng ,Prasanna Babu Araveti ,Ming Lo ,Igor Gavrish ,Aoife K O'Connell ,Hans P Gertje ,Anna C Belkina ,Colleen E Thurman ,Hirofumi Kiyokawa ,Darrell Kotton ,Shumin Tan ,Janice J Endsley ,William R Bishai ,Nicholas Crossland ,Lester Kobzik ,Igor Kramnik

Immune signatures of SARS-CoV-2 infection resolution in human lung tissues

SARS-CoV-2感染在人肺组织中消退的免疫特征

Kenney, Devin; O'Connell, Aoife K; Tseng, Anna E; Turcinovic, Jacquelyn; Sheehan, Maegan L; Nitido, Adam D; Montanaro, Paige; Gertje, Hans P; Ericsson, Maria; Connor, John H; Vrbanac, Vladimir; Crossland, Nicholas A; Harly, Christelle; Balazs, Alejandro B; Douam, Florian

Receptor transporter protein 4 (RTP4)-mediated repression of hepatitis C virus replication in mouse cells

受体转运蛋白4 (RTP4) 介导的丙型肝炎病毒在小鼠细胞中的复制抑制

Schwoerer, Michael P; Carver, Sebastian; Lin, Aaron E; Liu, Jianche; Cafiero, Thomas R; Berggren, Keith A; Dhawan, Serene; Suzuki, Saori; Heller, Brigitte; Rodriguez, Celeste; O'Connell, Aoife K; Gertje, Hans P; Crossland, Nicholas A; Ploss, Alexander

Assessment of hepatitis C virus permissiveness in iteratively genetically humanized mice

对经迭代基因改造人源化小鼠的丙型肝炎病毒易感性进行评估

Schwoerer, Michael P; Carver, Sebastian; Cafiero, Thomas R; Joyce, Bradley; Berggren, Keith A; Suzuki, Saori; Heller, Brigitte; O'Connell, Aoife K; Gertje, Hans P; Crossland, Nicholas A; Posfai, Eszter; Ploss, Alexander

An Intranasal Challenge Model in African Green Monkeys (Chlorocebus aethiops) for Mild-to-Moderate COVID-19 Disease Caused by Subvariant XBB.1.5

非洲绿猴(Chlorocebus aethiops)鼻内感染模型研究由XBB.1.5亚型病毒引起的轻度至中度COVID-19疾病

Storm, Nadia; Lo, Ming; Crossland, Nicholas; Seyler-Schmidt, Margaux; Staples, Hilary; Silva-Ayala, Daniela; Laprise, Ambre M; St Denis, Lauren; Grosz, Kyle; O'Connell, Aoife; Gertje, Hans; Ripin, Tillie; Decker, Claire; Mazur, M; Thurman, Colleen; Espinoza, Marlene; Morrow, Gavin; Parks, Christopher L; Cooper, Christopher L; Griffiths, Anthony

Protocol for 3D multiplexed fluorescent imaging of pulmonary TB lesions using Opal-TSA dyes for signal amplification

使用 Opal-TSA 染料进行信号放大的肺结核病变 3D 多重荧光成像协议

Suruchi Lata, Shivraj M Yabaji, Aoife K O'Connell, Hans P Gertje, Michael T Kirber, Nicholas A Crossland, Igor Kramnik

Protocol for developing a mouse model of post-primary pulmonary tuberculosis after hematogenous spread in native lungs and lung implants.

建立小鼠原发性肺结核血源性播散至原发肺和肺移植模型的方案

Yabaji Shivraj M, Lata Suruchi, Gavrish Igor, Lo Ming, O'Connell Aoife K, Gertje Hans P, Thurman Colleen E, Crossland Nicholas A, Kobzik Lester, Kramnik Igor

Sub-phenotypes of pneumonia defined by pulmonary histopathological features

根据肺部组织病理学特征定义的肺炎亚型

Shastry, Amulya; Hiller, Bradley E; Sanders, Nathan L; Tseng, Anna E; Kothari, Jeet; O'Connell, Aoife K; Gertje, Hans P; Ha, Catherine T; Murzin, Ekaterina; Traber, Katrina E; Lederer, James A; Jones, Mattthew R; Douam, Florian; Beach, Thomas G; Remick, Daniel G; Crossland, Nicholas A; Monti, Stefano; Campbell, Joshua D; Mizgerd, Joseph P