日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Curcumin Combined with FOLFOX Chemotherapy Is Safe and Tolerable in Patients with Metastatic Colorectal Cancer in a Randomized Phase IIa Trial.

在一项随机 IIa 期试验中,姜黄素联合 FOLFOX 化疗对转移性结直肠癌患者安全且耐受性良好

Howells Lynne M, Iwuji Chinenye O O, Irving Glen R B, Barber Shaun, Walter Harriet, Sidat Zahirah, Griffin-Teall Nicola, Singh Rajinder, Foreman Nalini, Patel Samita R, Morgan Bruno, Steward William P, Gescher Andreas, Thomas Anne L, Brown Karen

Prolonged biologically active colonic tissue levels of curcumin achieved after oral administration--a clinical pilot study including assessment of patient acceptability.

口服给药后,姜黄素在结肠组织中达到持久的生物活性水平——一项包括患者接受度评估的临床试验研究

Irving Glen R B, Howells Lynne M, Sale Stewart, Kralj-Hans Ines, Atkin Wendy S, Clark Susan K, Britton Robert G, Jones Donald J L, Scott Edwina N, Berry David P, Hemingway David, Miller Andrew S, Brown Karen, Gescher Andreas J, Steward William P

Preclinical colorectal cancer chemopreventive efficacy and p53-modulating activity of 3',4',5'-trimethoxyflavonol, a quercetin analogue.

槲皮素类似物 3',4',5'-三甲氧基黄酮醇的临床前结直肠癌化学预防功效和 p53 调节活性

Howells Lynne M, Britton Robert G, Mazzoletti Marco, Greaves Peter, Broggini Massimo, Brown Karen, Steward William P, Gescher Andreas J, Sale Stewart

PPARdelta status and mismatch repair mediated neoplasia in the mouse intestine

PPARδ状态与错配修复介导的小鼠肠道肿瘤形成

Reed, Karen R; Sansom, Owen J; Hayes, Anthony J; Gescher, Andreas J; Peters, Jeffrey M; Clarke, Alan R

Growth-inhibitory effects of the chemopreventive agent indole-3-carbinol are increased in combination with the polyamine putrescine in the SW480 colon tumour cell line

在SW480结肠肿瘤细胞系中,化学预防剂吲哚-3-甲醇与多胺腐胺联合使用可增强其生长抑制作用。

Hudson, E Ann; Howells, Lynne M; Gallacher-Horley, Barbara; Fox, Louise H; Gescher, Andreas; Manson, Margaret M