PKM splice-switching ASOs induce upregulation of dual-specificity phosphatases and dephosphorylation of ERK1/2 in hepatocellular carcinoma
PKM剪接转换反义寡核苷酸诱导肝细胞癌中双特异性磷酸酶上调和ERK1/2去磷酸化
期刊:Journal of Biological Chemistry
影响因子:3.9
doi:10.1016/j.jbc.2025.108345
Voss, Dillon M; Kral, Alexander J; Sim, GeunYoung; Utama, Raditya; Lin, Kuan-Ting; Cizmeciyan, Chris; Schafer, Balazs; Cunniff, Patrick J; Vakoc, Christopher R; Caruthers, Marvin H; Mishra, Lopa; Krainer, Adrian R
肿瘤
肿瘤免疫
信号转导
MAPK/ERK
磷酸化
细胞生物学