日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Cleavage at the nsp5-nsp6 site of SARS-CoV-2 main protease intermediate precursor is faster from a monomer than a dimer form

SARS-CoV-2 主蛋白酶中间体前体在 nsp5-nsp6 位点的切割,单体形式的切割速度比二聚体形式更快。

Aniana, Annie; Nashed, Nashaat T; Ghirlando, Rodolfo; Bhandari, Dipendra; Kovalevsky, Andrey; Louis, John M

Activity of the mammalian DNA transposon piggyBat from Myotis lucifugus is restricted by its own transposon ends

来自小棕蝠(Myotis lucifugus)的哺乳动物DNA转座子piggyBat的活性受到其自身转座子末端的限制。

Hickman, Alison B; Lannes, Laurie; Furman, Christopher M; Hong, Christina; Franklin, Lidiya; Ghirlando, Rodolfo; Ghosh, Arpita; Luo, Wentian; Konstantinidou, Parthena; Lorenzi, Hernán A; Grove, Anne; Haase, Astrid D; Wilson, Matthew H; Dyda, Fred

Cryo-EM structures of the E. coli Ton and Tol motor complexes

大肠杆菌Ton和Tol马达复合物的冷冻电镜结构

Celia, Herve; Botos, Istvan; Ghirlando, Rodolfo; Duché, Denis; Beach, Bridgette M; Lloubes, Roland; Buchanan, Susan K

Structural details of helix-mediated multimerization of the conserved region of TDP-43 C-terminal domain

TDP-43 C端结构域保守区螺旋介导多聚化的结构细节

Rizuan, Azamat; Shenoy, Jayakrishna; Mohanty, Priyesh; Dos Passos, Patricia M; Mercado Ortiz, José F; Bai, Leanna; Viswanathan, Renjith; Zaborowksy, Julia; Wang, Szu-Huan; Johnson, Victoria; Mamede, Lohany D; Titus, Amanda R; Ayala, Yuna M; Ghirlando, Rodolfo; Mittal, Jeetain; Fawzi, Nicolas L

Structural basis of double-stranded RNA recognition by the J2 monoclonal antibody

J2单克隆抗体识别双链RNA的结构基础

Bou-Nader, Charles; Juma, Kevin M; Bothra, Ankur; Brasington, Andrew J; Ghirlando, Rodolfo; Suzuki, Motoshi; Garboczi, David N; Leppla, Stephen H; Zhang, Jinwei

HIV-1 vif mediates ubiquitination of the proximal protomer in the APOBEC3H dimer to induce degradation

HIV-1 vif介导APOBEC3H二聚体近端亚基的泛素化,从而诱导其降解。

Katarzyna A Skorupka #,Kazuhiro Matsuoka #,Bakar Hassan,Rodolfo Ghirlando,Vanivilasini Balachandran,Ting-Hua Chen,Kylie J Walters,Celia A Schiffer,Matthias Wolf,Yasumasa Iwatani,Hiroshi Matsuo

Asymmetric loading of TnsE regulates Tn7 targeting of DNA replication structures

TnsE 的不对称加载调控 Tn7 对 DNA 复制结构的靶向作用

Krishnan, Shreya S; Shen, Yao; O'Hagan, Treasa B; Matthews, Lindsay A; Weerasinghe, Nuwani W; Ghirlando, Rodolfo; Thibodeaux, Christopher J; Guarné, Alba

Structural insights into Cir-mediated killing by the antimicrobial protein Microcin V

抗菌蛋白Microcin V介导的Cir杀菌作用的结构解析

Maurakis, Stavros A; O'Donnell, Angela C; Botos, Istvan; Ghirlando, Rodolfo; Davies, Bryan W; Buchanan, Susan K

Characterization of an unusual SARS-CoV-2 main protease natural variant exhibiting resistance to nirmatrelvir and ensitrelvir.

对一种不寻常的 SARS-CoV-2 主蛋白酶天然变体进行表征,该变体对 nirmatrelvir 和 ensitrelvir 具有耐药性

Bhandari Dipendra, Gerlits Oksana, Keable Stephen, Coates Leighton, Aniana Annie, Ghirlando Rodolfo, Nashed Nashaat T, Kovalevsky Andrey, Louis John M

Specificity and mechanism of the double-stranded RNA-specific J2 monoclonal antibody

双链RNA特异性J2单克隆抗体的特异性和机制

Bou-Nader, Charles; Juma, Kevin M; Bothra, Ankur; Brasington, Andrew J; Ghirlando, Rodolfo; Suzuki, Motoshi; Garboczi, David N; Leppla, Stephen H; Zhang, Jinwei