日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Liver Steatosis in Induced Hepatocytes From Carriers of Spinal Muscular Atrophy

脊髓性肌萎缩症携带者诱导肝细胞的肝脂肪变性

Sun, Lingyu; Leow, Damien Meng Kiat; Wang, Loo Chien; Eio, Michelle Yating; Koh, Hiromi W L; Khong, Zi Jian; Narayanan, Gunaseelan; Teo, Aloysius Kai Soon; Giadone, Richard; Sobota, Radoslaw M; Ng, Shi Yan; Teo, Adrian Kee Keong; Ong, Wei Yi; Rubin, Lee L; Darras, Basil T; Yeo, Crystal J J

Microbiome depletion rejuvenates the aging brain

微生物群的减少可以使衰老的大脑恢复活力

Gasperini, C; Holton, K M; Limone, F; Juttu, M; DeMeo, C C; Kekrtova, K; Patankar, S; Wells, K M; Giadone, R M; Driss, L Ben; Wei, G; Kiem, A; Xu, Q; Lee, R T; Friedlander, M; Scadden, D T; Rubin, L L

Author Correction: Heterochronic parabiosis reprograms the mouse brain transcriptome by shifting aging signatures in multiple cell types

作者更正:异时共生通过改变多种细胞类型中的衰老特征来重编程小鼠大脑转录组

Ximerakis, Methodios; Holton, Kristina M; Giadone, Richard M; Ozek, Ceren; Saxena, Monika; Santiago, Samara; Adiconis, Xian; Dionne, Danielle; Nguyen, Lan; Shah, Kavya M; Goldstein, Jill M; Gasperini, Caterina; Gampierakis, Ioannis A; Lipnick, Scott L; Simmons, Sean K; Buchanan, Sean M; Wagers, Amy J; Regev, Aviv; Levin, Joshua Z; Rubin, Lee L

A longevity-specific bank of induced pluripotent stem cells from centenarians and their offspring

一个专门针对长寿的诱导多能干细胞库,这些干细胞来自百岁老人及其后代

Todd W Dowrey ,Samuel F Cranston ,Nicholas Skvir ,Yvonne Lok ,Brian Gould ,Bradley Petrowitz ,Daniel Villar ,Jidong Shan ,Marianne James ,Mark Dodge ,Anna C Belkina ,Richard M Giadone ,Sofiya Milman ,Paola Sebastiani ,Thomas T Perls ,Stacy L Andersen ,George J Murphy

An induced pluripotent stem cell-based chemical genetic approach for studying spinal muscular atrophy

一种基于诱导多能干细胞的化学遗传学方法在脊髓性肌萎缩症研究中的应用

Giadone, Richard M; Holton, Kristina M; Hu, Xiaoyu; Natoli, Ted; Ghosh, Sabrina; Gill, Stanley P; Lyons, Nicholas; Subramanian, Aravind; Rubin, Lee L

Sex differences in motivation to take sucrose following abstinence and environmental enrichment in Long-Evans rats

Long-Evans大鼠在戒断和环境丰富化后摄入蔗糖的动机存在性别差异

Grimm, Jeffrey W; Sauter, Frances; MacDougall, Derek; Spaulding, Emily; Giadone, Sarah; Stensgaard, Kyra; Hardy, Mason

An induced pluripotent stem cell-based chemical genetic approach for studying spinal muscular atrophy

一种基于诱导多能干细胞的化学遗传学方法在脊髓性肌萎缩症研究中的应用

Giadone, Richard M; Holton, Kristina M; Hu, Xiaoyu; Natoli, Ted; Ghosh, Sabrina; Gill, Stanley P; Subramanian, Aravind; Rubin, Lee L

Hepatocyte-intrinsic SMN deficiency drives metabolic dysfunction and liver steatosis in spinal muscular atrophy

肝细胞内在 SMN 缺乏导致脊髓性肌萎缩症中的代谢功能障碍和肝脏脂肪变性

Damien Meng-Kiat Leow, Yang Kai Ng, Loo Chien Wang, Hiromi Wl Koh, Tianyun Zhao, Zi Jian Khong, Tommaso Tabaglio, Gunaseelan Narayanan, Richard M Giadone, Radoslaw M Sobota, Shi-Yan Ng, Adrian Kk Teo, Simon H Parson, Lee L Rubin, Wei-Yi Ong, Basil T Darras, Crystal Jj Yeo

Analyzing the ER stress response in ALS patient derived motor neurons identifies druggable neuroprotective targets

分析ALS患者运动神经元中的内质网应激反应,可识别出可作为药物靶点的神经保护靶点。

Michelle E Watts ,Richard M Giadone ,Alban Ordureau # ,Kristina M Holton ,J Wade Harper ,Lee L Rubin

Abnormal global longitudinal strain and reduced serum inflammatory markers in cardiac AL amyloidosis patients without significant amyloid fibril deposition

心脏AL淀粉样变性患者(无明显淀粉样蛋白原纤维沉积)存在异常的整体纵向应变和血清炎症标志物降低。

Edwards, Camille V; Ferri, Grace M; Villegas-Galaviz, Josue; Ghosh, Sabrina; Bawa, Pushpinder Singh; Wang, Feiya; Klimtchuk, Elena; Ajayi, Tinuola B; Morgan, Gareth J; Prokaeva, Tatiana; Staron, Andrew; Ruberg, Frederick L; Sanchorawala, Vaishali; Giadone, Richard M; Murphy, George J