Patients with STAT1 Gain-of-function Mutations Display Increased Apoptosis which is Reversed by the JAK Inhibitor Ruxolitinib
STAT1 功能获得性突变患者表现出细胞凋亡增加，而 JAK 抑制剂鲁索替尼可逆转这一现象。
期刊:Journal of Clinical Immunology
影响因子:5.7
doi:10.1007/s10875-024-01684-y
Dotta, Laura; Todaro, Francesca; Baronio, Manuela; Giacomelli, Mauro; Pinelli, Marinella; Giambarda, Martina; Brognoli, Beatrice; Greco, Silvia; Rota, Francesca; Cortesi, Manuela; Soresina, Annarosa; Moratto, Daniele; Tomasi, Cesare; Ferraro, Rosalba Monica; Giliani, Silvia; Badolato, Raffaele
凋亡
STAT1
表观遗传
Apoptosis
JAK/STAT
细胞生物学
