日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Single nuclei and spatial profiling of sacrococcygeal teratomas reveals cellular composition and X inactivation heterogeneity.

骶尾部畸胎瘤的单核和空间分析揭示了细胞组成和 X 染色体失活的异质性。

期刊:npj Precision Oncology
影响因子:8
doi:10.1038/s41698-025-01262-4
Rojas Ernesto J, Giannikou Krinio, Huang Benjamin J, Cho Soo-Jin, Cordero Marco A, Pena Deion, Vu Lan, Bagrodia Aditya, Derderian S Christopher, MacKenzie Tippi C, Laird Diana J
细胞生物学
发表日期：2026
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Spatial Profiling Identifies Tumor-Associated Stroma Enrichment and MIF as Potential Immunotherapy Targets in Primary Ewing Sarcomas

空间分析发现肿瘤相关基质富集和MIF是原发性尤文氏肉瘤潜在的免疫治疗靶点

期刊:Clinical Cancer Research
影响因子:10.2
doi:10.1158/1078-0432.CCR-25-0635
Kuo, Christopher; Giannikou, Krinio; Wang, Nuoya; Warren, Mikako; Goodspeed, Andrew; Shillingford, Nick; Hayashi, Masanori; Raredon, Micha Sam Brickman; Amatruda, James F
肿瘤
MIF
肿瘤免疫
免疫/内分泌
发表日期：2025
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Molecular Features and Actionable Gene Targets of Testicular Germ Cell Tumors in a Real-World Setting

真实世界环境下睾丸生殖细胞肿瘤的分子特征和可靶向基因

期刊:International Journal of Molecular Sciences
影响因子:4.9
doi:10.3390/ijms26188963
Morales-Grimany, Rafael; Giannikou, Krinio; Delgado, Cesar; Pandit, Kshitij; Baky, Fady; Amini, Armon; Yuen, Kit; Gerald, Thomas; Badia, Rohit; Taylor, Jacob; Wang, Luke; Javier-Desloges, Juan; Margulis, Vitaly; Woldu, Solomon; Salmasi, Amirali; Millard, Fred; Mckay, Rana R; Bagrodia, Aditya
细胞生物学
肿瘤
肿瘤免疫
发表日期：2025
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Tumor-associated stroma shapes the spatial tumor immune microenvironment of primary Ewing sarcomas

肿瘤相关基质塑造了原发性尤文氏肉瘤的空间肿瘤免疫微环境

期刊:
影响因子:
doi:10.1101/2025.01.31.635996
Kuo, Christopher; Giannikou, Krinio; Wang, Nuoya; Warren, Mikako; Goodspeed, Andrew; Shillingford, Nick; Hayashi, Masanori; Raredon, Micha Sam Brickman; Amatruda, James F
肿瘤
肿瘤免疫
免疫/内分泌
发表日期：2025
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Integrated single-nuclei and spatial transcriptomic profiling of human sacrococcygeal teratomas reveals heterogeneity in cellular composition and X-chromosome inactivation.

对人类骶尾部畸胎瘤进行单核和空间转录组分析，揭示了细胞组成和 X 染色体失活的异质性。

期刊:
影响因子:
doi:10.1101/2025.07.21.665156
Rojas Ernesto J, Giannikou Krinio, Huang Benjamin J, Cho Soo-Jin, Cordero Marco A, Pena Deion, Vu Lan, Bagrodia Aditya, Derderian S Christopher, MacKenzie Tippi C, Laird Diana J
细胞生物学
发表日期：2025
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Driver mutations associated with signatures of platinum sensitivity in germ cell tumors

与生殖细胞肿瘤铂类药物敏感性特征相关的驱动基因突变

期刊:npj Precision Oncology
影响因子:8
doi:10.1038/s41698-024-00727-2
Sawa, Yun Cheng; Jia, Liwei; Krause, Harris; Meagher, Margaret; Millard, Frederick; Elliott, Andrew; Lafin, John T; Jamieson, Christina; Antonarakis, Emmanuel S; D'Souza, Anishka; Giannikou, Krinio; Amatruda, James F; Daneshmand, Siamak; McKay, Rana R; Oberley, Matthew; Nabhan, Chadi; Bagrodia, Aditya
细胞生物学
肿瘤
肿瘤免疫
发表日期：2024
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Comprehensive genetic and phenotype analysis of 95 individuals with mosaic tuberous sclerosis complex

对95例嵌合型结节性硬化症患者进行全面的遗传和表型分析

期刊:American Journal of Human Genetics
影响因子:8.1
doi:10.1016/j.ajhg.2023.04.002
Klonowska, Katarzyna; Giannikou, Krinio; Grevelink, Joannes M; Boeszoermenyi, Barbara; Thorner, Aaron R; Herbert, Zachary T; Afrin, Antara; Treichel, Alison M; Hamieh, Lana; Kotulska, Katarzyna; Jozwiak, Sergiusz; Moss, Joel; Darling, Thomas N; Kwiatkowski, David J
发表日期：2023
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Ultrasensitive profiling of UV-induced mutations identifies thousands of subclinical facial tumors in tuberous sclerosis complex.

对紫外线诱发突变的超灵敏分析可识别结节性硬化症患者面部数千个亚临床肿瘤

期刊:Journal of Clinical Investigation
影响因子:13.6
doi:10.1172/JCI155858
Klonowska Katarzyna, Grevelink Joannes M, Giannikou Krinio, Ogorek Barbara A, Herbert Zachary T, Thorner Aaron R, Darling Thomas N, Moss Joel, Kwiatkowski David J
肿瘤
肿瘤免疫
发表日期：2022
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Spectrum of germline and somatic mitochondrial DNA variants in Tuberous Sclerosis Complex

结节性硬化症中种系和体细胞线粒体DNA变异谱

期刊:Frontiers in Genetics
影响因子:2.8
doi:10.3389/fgene.2022.917993
Giannikou, Krinio; Martin, Katie R; Abdel-Azim, Ahmad G; Pamir, Kaila J; Hougard, Thomas R; Bagwe, Shefali; Tang, Yan; MacKeigan, Jeffrey P; Kwiatkowski, David J; Henske, Elizabeth P; Lam, Hilaire C
细胞生物学
线粒体
发表日期：2022
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Therapeutic Targeting of DGKA-Mediated Macropinocytosis Leads to Phospholipid Reprogramming in Tuberous Sclerosis Complex

靶向DGKA介导的巨胞饮作用可导致结节性硬化症复合体中的磷脂重编程

期刊:Cancer Research
影响因子:16.6
doi:10.1158/0008-5472.CAN-20-2218
Kovalenko, Andrii; Sanin, Andres; Kosmas, Kosmas; Zhang, Long; Wang, Ji; Akl, Elie W; Giannikou, Krinio; Probst, Clemens K; Hougard, Thomas R; Rue, Ryan W; Krymskaya, Vera P; Asara, John M; Lam, Hilaire C; Kwiatkowski, David J; Henske, Elizabeth P; Filippakis, Harilaos
发表日期：2021
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