Paired primary-metastasis patient-derived organoids and mouse models identify phenotypic evolution and druggable dependencies of peritoneal metastasis from appendiceal cancer.
配对的原发转移患者来源的类器官和鼠模型揭示了阑尾癌腹膜转移的表型演变和药物依赖性
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doi:10.1101/2025.02.17.638725
Mahmoud Ahmed, Choi Philip H, Sukhwa Christine, Pintar Jura, Walch Henry, Zhao Nan, Bermeo Jonathan, Chung Sebastian, Raghavan Manisha, Bapat Samhita, Jiang Qingwen, Karagkounis Georgios, Meredith Julia, Giarrizzo Michael, Firat Canan, Cercek Andrea, Foote Michael B, Schultz Nikolaus, Chatila Walid K, Nash Garrett M, Shia Jinru, Sanchez-Vega Francisco, Larson Steven, Dar Arvin C, Rosen Neal, Ganesh Karuna
