日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

C1q-dependent clearance of alpha-synuclein allows macrophages to transiently limit enteric synucleinopathy in male mice

C1q依赖性α-突触核蛋白清除作用使巨噬细胞能够暂时性地限制雄性小鼠的肠道突触核蛋白病。

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-026-68641-8
Mackie, Phillip M; Koshy, Joanne M; Bhogade, Mauli H; Hammoor, Tristan; Hachmeister, William; Lloyd, Grace M; Paterno, Giavanna; Bolen, Mackenzie L; Merchak, Andrea; Gamez-Tansey, Malu; Giasson, Benoit I; Khoshbouei, Habibeh
巨噬细胞
细胞生物学
神经科学
巨噬细胞
免疫/内分泌
发表日期：2026
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Rigorous evaluation of pathological α-synucleinopathy transmissibility between animals in an experimental model

在实验模型中对动物间病理性α-突触核蛋白病的传播性进行严格评估

期刊:Acta Neuropathologica Communications
影响因子:5.7
doi:10.1186/s40478-026-02268-0
Sacino, Amanda N; Golde, Todd E; Borchelt, David R; Giasson, Benoit I; Moehle, Mark S
神经科学
发表日期：2026
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Progressive Supranuclear Palsy PERK Haplotype B Selectively Translates DLX1 Promoting Tau Toxicity

进行性核上性麻痹症 PERK 单倍型 B 选择性翻译 DLX1 促进 Tau 毒性

期刊:Journal of Neuroscience
影响因子:4
doi:10.1523/JNEUROSCI.1727-25.2026
Lessard, Christian B; Rubio Rubio, Diego; Tolton, Samantha; Criado-Marrero, Marangelie; Ravi, Sakthivel; Garza, Tristyn N; Koren, John; Philips, Jennifer; Bagchi, Pritha; McFarland, Karen; Chhangani, Deepak; Golde, Todd E; Giasson, Benoit I; Lewis, Jada; Chakrabarty, Paramita; LaVoie, Matthew J; Borchelt, David R; Seyfried, Nicholas T; Prokop, Stefan; Rincon-Limas, Diego E; Abisambra, Jose F
MAPK/ERK
PERK
毒理研究
发表日期：2026
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A novel pThr217 tau monoclonal antibody reveals neuropathological heterogeneity in tauopathies

新型pThr217 tau单克隆抗体揭示tau蛋白病中的神经病理学异质性

期刊:Scientific Reports
影响因子:3.9
doi:10.1038/s41598-025-04291-y
Paterno, Giavanna; Bell, Brach M; Gorion, Kimberly-Marie M; Quintin, Stephan; Prokop, Stefan; Giasson, Benoit I
单克隆抗体
发表日期：2025
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Uncovering α-synuclein and tau burden in Alzheimer's and Lewy body diseases

揭示阿尔茨海默病和路易体病中的α-突触核蛋白和tau蛋白负荷

期刊:Brain Communications
影响因子:
doi:10.1093/braincomms/fcaf324
Quintin, Stephan; Paterno, Giavanna; Lloyd, Grace M; Prokop, Stefan; Giasson, Benoit I
阿尔茨海默症
神经科学
发表日期：2025
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Correction: Collusion of α-Synuclein and Aβ aggravating co-morbidities in a novel prion-type mouse model

更正：α-突触核蛋白和Aβ的协同作用加剧了新型朊病毒型小鼠模型中的合并症

期刊:Molecular Neurodegeneration
影响因子:17.5
doi:10.1186/s13024-024-00710-2
Lloyd, Grace M; Dhillon, Jess-Karan S; Gorion, Kimberly-Marie M; Riffe, Cara; Fromholt, Susan E; Xia, Yuxing; Giasson, Benoit I; Borchelt, David R
微生物学
神经科学
发表日期：2024
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A multiverse of α-synuclein: investigation of prion strain properties with carboxyl-terminal truncation specific antibodies in animal models

α-突触核蛋白的多元宇宙：利用羧基末端截短特异性抗体在动物模型中研究朊病毒株的特性

期刊:Acta Neuropathologica Communications
影响因子:5.7
doi:10.1186/s40478-024-01805-z
Lloyd, Grace M; Quintin, Stephan; Sorrentino, Zachary A; Gorion, Kimberly-Marie M; Bell, Brach M; Long, Brooke; Paterno, Giavanna; Giasson, Benoit I
微生物学
神经科学
发表日期：2024
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Novel Monoclonal Antibody Specific toward Amyloid-β Binds to a Unique Epitope within the N-Terminal Region

一种新型的针对β-淀粉样蛋白的单克隆抗体，可结合N端区域内的独特表位。

期刊:Antibodies
影响因子:2.7
doi:10.3390/antib13030068
Paterno, Giavanna; Moore, Brenda D; Bell, Brach M; Gorion, Kimberly-Marie M; Ran, Yong; Prokop, Stefan; Golde, Todd E; Giasson, Benoit I
单克隆抗体
发表日期：2024
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Carboxyl truncation of α-synuclein occurs early and is influenced by human APOE genotype in transgenic mouse models of α-synuclein pathogenesis

α-突触核蛋白的羧基截断发生较早，并且在α-突触核蛋白致病性的转基因小鼠模型中受人类APOE基因型的影响。

期刊:Acta Neuropathologica Communications
影响因子:5.7
doi:10.1186/s40478-023-01623-9
Lloyd, Grace M; Long, Brooke; Quintin, Stephan; Sorrentino, Zachary A; Gorion, Kimberly-Marie M; Bell, Brach M; Carrillo, Denise; Sullivan, Patrick; Borchelt, David; Giasson, Benoit I
APOE
神经科学
发表日期：2023
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Novel Conformation-Dependent Tau Antibodies Are Modulated by Adjacent Phosphorylation Sites

新型构象依赖性Tau抗体受邻近磷酸化位点调控

期刊:International Journal of Molecular Sciences
影响因子:4.9
doi:10.3390/ijms241813676
Paterno, Giavanna; Torrellas, Jose; Bell, Brach M; Gorion, Kimberly-Marie M; Quintin, Stephan S; Hery, Gabriela P; Prokop, Stefan; Giasson, Benoit I
信号转导
磷酸化
发表日期：2023
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