Impaired DNA damage responses and inflammatory signaling underpin hematopoietic stem cell defects in Gata2 haploinsufficiency
Gata2单倍体不足导致造血干细胞缺陷的根本原因是DNA损伤反应和炎症信号传导受损。
期刊:Stem Cell Reports
影响因子:5.1
doi:10.1016/j.stemcr.2025.102596
Abdelfattah, Ali; Habib, Ahmad; Thomas, Leigh-Anne; Menendez-Gonzalez, Juan Bautista; Almotiri, Alhomidi; Alqahtani, Hind; Lawson, Hannah; Taha, Sarab; Steadman, Millie; Athalye, Radhika; Gibbs, Alex; Alzahrani, Hamed; Alshahrani, Ali; Cato, Alice; Giles, Peter; Tonks, Alex; Boyd, Ashleigh S; Kranc, Kamil R; Rodrigues, Neil P
发育与干细胞
炎症
炎症/感染
信号转导
干细胞
细胞生物学
毒理研究
