文献库，生知库 | 链接生命科学的每一步

日期影响因子

Suppressing t(4;11) Acute Leukemia by Lipopolymer Nanoparticle Delivery of siRNA Targeting KMT2A::AFF1 with Enhanced Extrahepatic Delivery

利用脂质体纳米颗粒递送靶向KMT2A::AFF1的siRNA抑制t(4;11)急性白血病并增强肝外递送

期刊:Advanced Healthcare Materials

影响因子:9.6

doi:10.1002/adhm.202502019

Nasrullah, Mohammad; Kc, Remant; Rajendran, Amarnath Praphakar; Dezfouli, Saba Abbasi; Kucharski, Cezary; Jiang, Xiaoyan; Gibson, Spencer B; Brandwein, Joseph; Heidenreich, Olaf; Uludağ, Hasan

发表日期：2025

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Saturated fatty acids induce lipotoxicity in lymphatic endothelial cells contributing to secondary lymphedema development.

饱和脂肪酸可诱导淋巴管内皮细胞产生脂毒性，从而导致继发性淋巴水肿的发生

期刊:EMBO Molecular Medicine

影响因子:8.3

doi:10.1038/s44321-025-00286-4

Gomes Karina P, Korodimas Jacob, Liu Emily, Patel Nirav, Yang Xiaoyan, Goruk Susan, Munhoz Jaqueline, Field Catherine J, Gibson Spencer B

细胞生物学

发表日期：2025

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ATM inhibition decreases ERK activation and is synergistic with ibrutinib in primary chronic lymphocytic leukemia cells

ATM抑制剂可降低ERK活化，并与伊布替尼在原发性慢性淋巴细胞白血病细胞中具有协同作用。

期刊:Blood Advances

影响因子:7.1

doi:10.1182/bloodadvances.2024014407

Kost, Sara E F; Saleh, Ali; Brown, Jennifer; Yuan, Shek H; Kuzio, Bozena; Yang, Lin; Banerji, Versha; Gibson, Spencer B; Johnston, James B; Katyal, Sachin

细胞生物学

发表日期：2025

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Polyfunctional CD8(+)CD226(+)RUNX2(hi) effector T cells are diminished in advanced stages of chronic lymphocytic leukemia

慢性淋巴细胞白血病晚期，多功能CD8(+)CD226(+)RUNX2(hi)效应T细胞减少。

期刊:Molecular Oncology

影响因子:4.5

doi:10.1002/1878-0261.13793

Rezaeifar, Maryam; Shahbaz, Shima; Peters, Anthea C; Gibson, Spencer B; Elahi, Shokrollah

细胞生物学

免疫/内分泌

发表日期：2025

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Lysosome targeted therapies in hematological malignancies

溶酶体靶向治疗在血液恶性肿瘤中的应用

期刊:Frontiers in Oncology

影响因子:3.3

doi:10.3389/fonc.2025.1549792

Manivannan, Madhumita S; Peters, Anthea; Gibson, Spencer B

发表日期：2025

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Breast Tumor Metastasis and Its Microenvironment: It Takes Both Seed and Soil to Grow a Tumor and Target It for Treatment

乳腺肿瘤转移及其微环境：肿瘤的生长和治疗靶向都需要种子和土壤

影响因子:4.4

doi:10.3390/cancers16050911

Bonni, Shirin; Brindley, David N; Chamberlain, M Dean; Daneshvar-Baghbadorani, Nima; Freywald, Andrew; Hemmings, Denise G; Hombach-Klonisch, Sabine; Klonisch, Thomas; Raouf, Afshin; Shemanko, Carrie Simone; Topolnitska, Diana; Visser, Kaitlyn; Vizeacoumar, Franco J; Wang, Edwin; Gibson, Spencer B

发表日期：2024

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DNA-PK hyperactivation occurs in deletion 11q chronic lymphocytic leukemia and is both a biomarker and therapeutic target for drug-resistant disease

DNA-PK过度激活发生于11q缺失型慢性淋巴细胞白血病中，既是耐药性疾病的生物标志物，也是治疗靶点。

期刊:Blood Cancer Journal

影响因子:11.6

doi:10.1038/s41408-022-00781-8

Kost, Sara E F; Saleh, Ali; Yuan, Shek H; Kuzio, Bozena; Gibson, Spencer B; Yang, Lin; Banerji, Versha; Johnston, James B; Katyal, Sachin

细胞生物学

发表日期：2023

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Clinical Outcomes in a Large Canadian Centralized CLL Clinic Based on Treatment and Molecular Factors over a Decade

加拿大一家大型集中式慢性淋巴细胞白血病诊所十年来基于治疗和分子因素的临床结果

期刊:Current Oncology

影响因子:3.4

doi:10.3390/curroncol30070472

Yang, Jiayu; Yang, Lin; Tordon, Bryan; Bucher, Oliver; Nugent, Zoann; Landego, Ivan; Bourrier, Nicole; Uminski, Kelsey; Brown, Kevin; Squires, Mandy; Marshall, Aaron J; Katyal, Sachin; Mahmud, Salah; Decker, Kathleen; Geirnaert, Marc; Dawe, David E; Gibson, Spencer B; Johnston, James B; Banerji, Versha

细胞生物学

发表日期：2023

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Venetoclax inhibits autophagy in chronic lymphocytic leukemia cells.

维奈托克抑制慢性淋巴细胞白血病细胞的自噬

期刊:Autophagy Reports

doi:10.1080/27694127.2023.2169518

Chen Yongqiang, Kost Sara E F, Yang Xiaoyan, Banerji Versha, Johnston James B, Katyal Sachin, Gibson Spencer B

细胞生物学

发表日期：2023

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Prostate Cancer Cells Are Sensitive to Lysosomotropic Agent Siramesine through Generation Reactive Oxygen Species and in Combination with Tyrosine Kinase Inhibitors.

前列腺癌细胞对溶酶体趋向剂西拉美辛敏感，可通过产生活性氧发挥作用，并与酪氨酸激酶抑制剂联合使用

影响因子:4.4

doi:10.3390/cancers14225478

Garcia Emily A, Bhatti Ilsa, Henson Elizabeth S, Gibson Spencer B

细胞生物学

发表日期：2022

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