日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

The nucleotide exchange factor, GrpE, modulates substrate affinity by interaction of its N-terminal tails with the DnaK substrate-binding domain

核苷酸交换因子GrpE通过其N端尾部与DnaK底物结合域的相互作用来调节底物亲和力。

Maqtedar, Akshitha; Rossi, Maria-Agustina; Clerico, Eugenia M; Williams, Robert V; Gierasch, Lila M

Model Peptides Enable Comparisons of Substrate Binding Modes of Hsp70 Molecular Chaperones

模型肽可用于比较Hsp70分子伴侣的底物结合模式

Bhasne, Karishma; Dörries, Lea; Maqtedar, Akshitha; Mager, Sydney T; Clerico, Eugenia M; Gierasch, Lila M

From Rat Tails to Glycoproteostasis: Motivated by Biology, Enabled by Biophysics, and Lucky

从鼠尾到糖蛋白稳态:生物学驱动,生物物理学促成,以及幸运

Gierasch, Lila M

The cysteine-rich domain of SEP15, a selenoprotein co-chaperone of the ER chaperone, UDP-glucose:glycoprotein glucosyltransferase, adopts a novel fold.

SEP15 是内质网伴侣蛋白 UDP-葡萄糖:糖蛋白葡萄糖基转移酶的硒蛋白辅助伴侣蛋白,其富含半胱氨酸的结构域采用了一种新的折叠方式

Williams Robert V, Guay Kevin P, Lesk Owen Hurlbut, Hebert Daniel N, Gierasch Lila M

New insights into the structure and function of the complex between the Escherichia coli Hsp70, DnaK, and its nucleotide-exchange factor, GrpE

对大肠杆菌 Hsp70、DnaK 及其核苷酸交换因子 GrpE 之间复合物的结构和功能的新见解

Maria-Agustina Rossi, Alexandra K Pozhidaeva, Eugenia M Clerico, Constantine Petridis, Lila M Gierasch

The Hsc70 system maintains the synaptic SNARE protein SNAP-25 in an assembly-competent state and delays its aggregation

Hsc70系统维持突触SNARE蛋白SNAP-25的组装活性状态,并延缓其聚集。

Bhasne, Karishma; Bogoian-Mullen, Antonia; Clerico, Eugenia M; Gierasch, Lila M

Second international symposium on the chaperone code, 2023

第二届国际陪护人员守则研讨会,2023年

Buchner, Johannes; Alasady, Milad J; Backe, Sarah J; Blagg, Brian S J; Carpenter, Richard L; Colombo, Giorgio; Gelis, Ioannis; Gewirth, Daniel T; Gierasch, Lila M; Houry, Walid A; Johnson, Jill L; Kang, Byoung Heon; Kao, Aimee W; LaPointe, Paul; Mattoo, Seema; McClellan, Amie J; Neckers, Leonard M; Prodromou, Chrisostomos; Rasola, Andrea; Sager, Rebecca A; Theodoraki, Maria A; Truman, Andrew W; Truttman, Matthias C; Zachara, Natasha E; Bourboulia, Dimitra; Mollapour, Mehdi; Woodford, Mark R

Multi-organ phenotypes in mice lacking latent TGFβ binding protein 2 (LTBP2)

缺乏潜伏性TGFβ结合蛋白2(LTBP2)的小鼠的多器官表型

Bodmer, Nicholas K; Knutsen, Russell H; Roth, Robyn A; Castile, Ryan M; Brodt, Michael D; Gierasch, Carrie M; Broekelmann, Thomas J; Gibson, Mark A; Haspel, Jeffrey A; Lake, Spencer P; Koenitzer, Jeffrey R; Brody, Steven L; Silva, Matthew J; Mecham, Robert P; Ornitz, David M

Monitoring the Secretion and Activity of Alpha-1 Antitrypsin in Various Mammalian Cell Types

监测各种哺乳动物细胞类型中 Alpha-1 抗胰蛋白酶的分泌和活性

Kevin P Guay, Haiping Ke, Lila M Gierasch, Anne Gershenson, Daniel N Hebert

Insights into the interaction between UGGT, the gatekeeper of folding in the ER, and its partner, the selenoprotein SEP15

深入了解内质网折叠守门人 UGGT 与其伴侣硒蛋白 SEP15 之间的相互作用

Robert V Williams, Kevin P Guay, Owen A Hurlbut Lesk, Eugenia M Clerico, Daniel N Hebert, Lila M Gierasch