日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Inhibiting HSP27 activates the XBP1s/CerS1 interplay, which triggers DRP1-driven mitophagy, thereby protecting against cell death and promoting the KSHV lytic cycle in primary effusion lymphoma cells.

抑制 HSP27 可激活 XBP1s/CerS1 相互作用，从而触发 DRP1 驱动的线粒体自噬，进而保护细胞免于死亡，并促进原发性渗出性淋巴瘤细胞中的 KSHV 裂解周期。

期刊:Cell Death Discovery
影响因子:7
doi:10.1038/s41420-026-02979-2
Gonnella Roberta, Corrado Vincenzo, Scaffidi Giulio Francesco, Benedetti Rossella, Di Crosta Michele, Zarrella Roberta, Gilardini Montani Maria Saveria, Santarelli Roberta, Cirone Mara
淋巴瘤
细胞生物学
DRP1
XBP1
线粒体
自噬
发表日期：2026
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Specific Bioelectrical Vector Reference Values for Italian Adults: A Multicentre Study

意大利成年人特定生物电向量参考值：一项多中心研究

期刊:Journal of Functional Morphology and Kinesiology
影响因子:2.5
doi:10.3390/jfmk11010081
Frau, Federica; Pizzo Junior, Eduardo; Succa, Valeria; Stagi, Silvia; Moro, Federica; Sguaizer, Francesco; Petri, Cristian; Paoli, Antonio; Mascherini, Gabriele; Izzicupo, Pascal; Bertoli, Simona; Gilardini, Luisa; Cavaggioni, Luca; Cereda, Emanuele; Campa, Francesco; Micheletti Cremasco, Margherita; Toselli, Stefania; Marini, Elisabetta
发表日期：2026
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Acetylation promotes mutant (MUT) TP53-HSPA8 and HSPA8-BAG3 interactions, facilitating MUT TP53 lysosomal degradation preferentially via CASA

乙酰化促进突变型（MUT）TP53-HSPA8和HSPA8-BAG3相互作用，从而优先通过CASA途径促进MUT TP53溶酶体降解。

期刊:Autophagy
影响因子:14.3
doi:10.1080/15548627.2025.2576615
Di Crosta, Michele; Ragone, Francesca Chiara; Benedetti, Rossella; D'Orazi, Gabriella; Santarelli, Roberta; Gonnella, Roberta; Gilardini Montani, Maria Saveria; Cirone, Mara
BAG3
乙酰化
表观遗传
P53
发表日期：2025
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Mutant p53 upregulates HDAC6 to resist ER stress and facilitates Ku70 deacetylation, which prevents its degradation and mitigates DNA damage in colon cancer cells.

突变型 p53 上调 HDAC6 以抵抗内质网应激，并促进 Ku70 去乙酰化，从而防止其降解并减轻结肠癌细胞中的 DNA 损伤

期刊:Cell Death Discovery
影响因子:7
doi:10.1038/s41420-025-02433-9
Benedetti Rossella, Di Crosta Michele, Gilardini Montani Maria Saveria, D'Orazi Gabriella, Cirone Mara
细胞生物学
肠癌
P53
乙酰化
发表日期：2025
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Effectiveness of a Digital Therapy on 6-Month Weight Loss in People With Obesity: The Digital Therapy to Promote Weight Loss in Patients With Obesity by Increasing Their Adherence to Treatment (DEMETRA) Randomized Clinical Trial

数字疗法对肥胖患者6个月减重效果的评估：通过提高治疗依从性促进肥胖患者减重的数字疗法（DEMETRA）随机临床试验

期刊:Journal of Medical Internet Research
影响因子:6
doi:10.2196/72054
Bertoli, Simona; Capodaglio, Paolo; Colosimo, Santo; De Amicis, Ramona Silvana; Gilardini, Luisa; Bruno, Amalia; Mambrini, Sara Paola; Pietrabissa, Giada; Cavaggioni, Luca; Castelnuovo, Gianluca; Piazzolla, Giuseppina
肥胖
MET
代谢
发表日期：2025
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Prenatal Delta-9-Tetrahydrocannabinol Exposure Induces Transcriptional Alterations in Dopaminergic System with Associated Electrophysiological Dysregulation in the Prefrontal Cortex of Adolescent Rats.

产前接触Δ-9-四氢大麻酚可诱导青春期大鼠前额皮质多巴胺能系统的转录改变，并伴有电生理失调

期刊:Cells
影响因子:5.2
doi:10.3390/cells14120904
Di Bartolomeo Martina, Aroni Sonia, Serra Marcello, Serra Valeria, Martella Francesca, Gilardini Federica, Melis Miriam, D'Addario Claudio
Rat
发表日期：2025
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Coordinated epigenetic dysregulation of CNR1 and FAAH genes drives endocannabinoid system dysfunction in anorexia nervosa

CNR1 和 FAAH 基因的协同表观遗传失调驱动神经性厌食症中的内源性大麻素系统功能障碍

期刊:Journal of Eating Disorders
影响因子:4.5
doi:10.1186/s40337-025-01472-y
Gilardini, Federica; Mercante, Francesca; Sabatucci, Annalaura; Pucci, Mariangela; Cifani, Carlo; Segura-Garcia, Cristina; Rania, Marianna; D'Addario, Claudio
表观遗传
发表日期：2025
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Changes in Lysine Methylation Contribute to the Cytotoxicity of Curcumin in Colon Cancer Cells

赖氨酸甲基化的变化导致姜黄素对结肠癌细胞产生细胞毒性

期刊:Molecules
影响因子:4.2
doi:10.3390/molecules30020335
Roberta Santarelli, Paola Currà, Michele Di Crosta, Roberta Gonnella, Maria Saveria Gilardini Montani, Mara Cirone
免疫
细胞生物学
肠癌
肿瘤细胞
DNA甲基化
SETD7
发表日期：2025
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Valemetostat-SAHA-Driven Acetylation of p53 via SET/TAF-Iβ Displacement and p300 Activation Modulates Cell Cycle Regulators in Pancreatic Cancer Cells

Valemetostat-SAHA通过SET/TAF-Iβ置换和p300激活驱动p53乙酰化，从而调节胰腺癌细胞中的细胞周期调节因子

期刊:Biomedicines
影响因子:3.9
doi:10.3390/biomedicines13092279
Di Crosta, Michele; Ragone, Francesca Chiara; Benedetti, Rossella; D'Orazi, Gabriella; Santarelli, Roberta; Gilardini Montani, Maria Saveria; Cirone, Mara
肿瘤
表观遗传
肿瘤免疫
细胞生物学
SET
乙酰化
胰腺癌
发表日期：2025
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Gender Differences in Weight Loss Extent Following Bariatric Surgery

减肥手术后体重减轻程度的性别差异

期刊:Journal of Clinical Medicine
影响因子:2.9
doi:10.3390/jcm14186605
Colosimo, Santo; Sileo, Federica; Gambetti, Andrea; Frattini, Francesco; Bruno, Amalia; Mambrini, Sara; Gilardini, Luisa; Barbera, Federica; Gotti, Alice; Vincenti, Verdiana; Inì, Laura; Novelli, Margherita; Cancello, Raffaella; Dionigi, Gianlorenzo; Bertoli, Simona
发表日期：2025
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