日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Antibody Structure and Function: The Basis for Engineering Therapeutics

抗体结构与功能:治疗工程的基础

Chiu, Mark L; Goulet, Dennis R; Teplyakov, Alexey; Gilliland, Gary L

Homology-based hydrogen bond information improves crystallographic structures in the PDB

基于同源性的氢键信息可以改进PDB中的晶体结构。

van Beusekom, Bart; Touw, Wouter G; Tatineni, Mahidhar; Somani, Sandeep; Rajagopal, Gunaretnam; Luo, Jinquan; Gilliland, Gary L; Perrakis, Anastassis; Joosten, Robbie P

A coiled conformation of amyloid-β recognized by antibody C706

抗体 C706 识别的淀粉样蛋白 β 的卷曲构象

Teplyakov, Alexey; Obmolova, Galina; Gilliland, Gary L

Functional, Biophysical, and Structural Characterization of Human IgG1 and IgG4 Fc Variants with Ablated Immune Functionality.

人类 IgG1 和 IgG4 Fc 变体的功能、生物物理和结构表征及其免疫功能的丧失

Tam Susan H, McCarthy Stephen G, Armstrong Anthony A, Somani Sandeep, Wu Sheng-Jiun, Liu Xuesong, Gervais Alexis, Ernst Robin, Saro Dorina, Decker Rose, Luo Jinquan, Gilliland Gary L, Chiu Mark L, Scallon Bernard J

Crystal structure of CD27 in complex with a neutralizing noncompeting antibody

CD27 与中和性非竞争性抗体的复合物晶体结构

Teplyakov, Alexey; Obmolova, Galina; Malia, Thomas J; Gilliland, Gary L

Structural diversity in a human antibody germline library.

人类抗体种系库的结构多样性

Teplyakov Alexey, Obmolova Galina, Malia Thomas J, Luo Jinquan, Muzammil Salman, Sweet Raymond, Almagro Juan Carlos, Gilliland Gary L

Epitope mapping and structural basis for the recognition of phosphorylated tau by the anti-tau antibody AT8

抗tau抗体AT8识别磷酸化tau蛋白的表位定位和结构基础

Malia, Thomas J; Teplyakov, Alexey; Ernst, Robin; Wu, Sheng-Jiun; Lacy, Eilyn R; Liu, Xuesong; Vandermeeren, Marc; Mercken, Marc; Luo, Jinquan; Sweet, Raymond W; Gilliland, Gary L

Induced conformational change in human IL-4 upon binding of a signal-neutralizing DARPin.

信号中和 DARPin 与人 IL-4 结合后诱导构象变化

Obmolova Galina, Teplyakov Alexey, Malia Thomas J, Keough Edward, Luo Jinquan, Sweet Raymond, Jacobs Steven A, Yi Fang, Hippensteel Randi, O'Neil Karyn T, Gilliland Gary L

Canonical structures of short CDR-L3 in antibodies

抗体中短CDR-L3的典型结构

Teplyakov, Alexey; Gilliland, Gary L

Protein crystallization with microseed matrix screening: application to human germline antibody Fabs

利用微晶基质筛选进行蛋白质结晶:应用于人类生殖系抗体Fab片段

Obmolova, Galina; Malia, Thomas J; Teplyakov, Alexey; Sweet, Raymond W; Gilliland, Gary L