日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Enzyme Activity-Based Genome-wide Screening for Modifiers of Lysosomal Glucocerebrosidase Uncovers Candidate Risk Factors for Parkinson's Disease

基于酶活性的全基因组溶酶体葡糖脑苷脂酶修饰因子筛选揭示帕金森病潜在风险因素

Udayar, Vinod; Gilormini, Pierre-André; Bryois, Julien; Gehrlein, Alexandra; Chen, Xi; Sonea, Stephanie; Zhu, Sha; Deen, Matthew C; Anastasi, Nadia; Murphy, Alan E; Skene, Nathan; Tan, Manuela M X; Tunold, Jon-Anders; Roudnicky, Filip; van de Berg, Wilma D J; Pihlstrøm, Lasse; Vocadlo, David J; Jagasia, Ravi

A gram-scale synthesis of β-L-carbafucose for engineering antibody glycans

用于抗体聚糖工程的β-L-碳酸岩藻糖的克级合成

Thota, V Narasimharao; Fers-Lidou, Anthony; Nodwell, Matthew; McDonagh, Anthony W; Gilormini, Pierre-André; Wang, Yang; Leung, Carolyn; Vocadlo, David J; Britton, Robert

Development of Tunable Mechanism-Based Carbasugar Ligands that Stabilize Glycoside Hydrolases through the Formation of Transient Covalent Intermediates

开发可通过形成瞬态共价中间体稳定糖苷水解酶的可调控机制型碳糖配体

Bhosale, Sandeep; Kandalkar, Sachin; Gilormini, Pierre-André; Akintola, Oluwafemi; Rowland, Rhianna; Adabala, Pal John Pal; King, Dustin; Deen, Matthew C; Chen, Xi; Davies, Gideon J; Vocadlo, David J; Bennet, Andrew J

A metabolic inhibitor blocks cellular fucosylation and enables production of afucosylated antibodies

代谢抑制剂可阻断细胞岩藻糖基化,从而产生无岩藻糖基化的抗体。

Gilormini, Pierre-André; Thota, V Narasimharao; Fers-Lidou, Anthony; Ashmus, Roger A; Nodwell, Matthew; Brockerman, Jacob; Kuo, Chu-Wei; Wang, Yang; Gray, Taylor E; Nitin; McDonagh, Anthony W; Guu, Shih-Yun; Ertunc, Nursah; Yeo, Dominick; Zandberg, Wesley F; Khoo, Kay-Hooi; Britton, Robert; Vocadlo, David J

Direct and indirect regulation of β-glucocerebrosidase by the transcription factors USF2 and ONECUT2

转录因子 USF2 和 ONECUT2 对 β-葡萄糖脑苷脂酶的直接和间接调控

Kathi Ging, Lukas Frick, Johannes Schlachetzki, Andrea Armani, Yanping Zhu, Pierre-André Gilormini, Ashutosh Dhingra, Desirée Böck, Ana Marques, Matthew Deen, Xi Chen, Tetiana Serdiuk, Chiara Trevisan, Stefano Sellitto, Claudio Pisano, Christopher K Glass, Peter Heutink, Jiang-An Yin, David J Vocadl

Quantifying lysosomal glycosidase activity within cells using bis-acetal substrates

使用双缩醛底物量化细胞内的溶酶体糖苷酶活性

Samy Cecioni #, Roger A Ashmus #, Pierre-André Gilormini, Sha Zhu, Xi Chen, Xiaoyang Shan, Christina Gros, Matthew C Deen, Yang Wang, Robert Britton, David J Vocadlo

A versatile fluorescence-quenched substrate for quantitative measurement of glucocerebrosidase activity within live cells

一种用途广泛的荧光猝灭底物,可用于定量测量活细胞内葡糖脑苷脂酶的活性。

Deen, Matthew C; Zhu, Yanping; Gros, Christina; Na, Na; Gilormini, Pierre-André; Shen, David L; Bhosale, Sandeep; Anastasi, Nadia; Wang, RuiQi; Shan, Xiaoyang; Harde, Eva; Jagasia, Ravi; Lynn, Francis C; Vocadlo, David J

Novel Zebrafish Mono-α2,8-sialyltransferase (ST8Sia VIII): An Evolutionary Perspective of α2,8-Sialylation

新型斑马鱼单-α2,8-唾液酸转移酶(ST8Sia VIII):α2,8-唾液酸化的进化视角

Chang, Lan-Yi; Teppa, Elin; Noel, Maxence; Gilormini, Pierre-André; Decloquement, Mathieu; Lion, Cédric; Biot, Christophe; Mir, Anne-Marie; Cogez, Virginie; Delannoy, Philippe; Khoo, Kay Hooi; Petit, Daniel; Guérardel, Yann; Harduin-Lepers, Anne

Asking more from metabolic oligosaccharide engineering

对代谢寡糖工程提出更高要求

Gilormini, Pierre-André; Batt, Anna R; Pratt, Matthew R; Biot, Christophe

Chemical glycomics enrichment: imaging the recycling of sialic acid in living cells

化学糖组学富集:对活细胞中唾液酸的循环利用进行成像

Gilormini, Pierre André; Lion, Cédric; Vicogne, Dorothée; Guérardel, Yann; Foulquier, François; Biot, Christophe