日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Acquired resistance in cancer: towards targeted therapeutic strategies

癌症获得性耐药:迈向靶向治疗策略

Soragni, Alice; Knudsen, Erik S; O'Connor, Thomas N; Tognon, Cristina E; Tyner, Jeffrey W; Gini, Beatrice; Kim, Donghwa; Bivona, Trever G; Zang, Xingxing; Witkiewicz, Agnieszka K; Goodrich, David W; Jiang, Dadi; Gammon, Seth T; Willey, Christopher D; Boutros, Paul C; Sandulache, Vlad C; Osman, Abdullah A; Myers, Jeffrey N; Mehla, Kamiya; Singh, Pankaj K; Chan, Keith S; Gao, Hongbo; Marathe, Himangi

CDK4 or CDK6 upregulation induces DNA replication stress and genomic instability to cause EGFR targeted therapy resistance in lung cancer

CDK4或CDK6的上调会诱导DNA复制压力和基因组不稳定性,从而导致肺癌中EGFR靶向治疗的耐药性。

Gini, Beatrice; Gui, Philippe; Wu, Wei; Lucas Kerr, D; Tan, Lisa; Barbosa, Dora; Olivas, Victor; Allegakoen, Paul; Gomez, Carlos; Halliday, Patrick R; Elmes, Sarah; Steri, Veronica; Chakrabarti, Turja; Bivona, Trever G; Blakely, Collin M

Perspectives on Open Science and The Future of Scholarly Communication: Internet Trackers and Algorithmic Persuasion

关于开放科学和学术交流未来的展望:互联网追踪器和算法说服

Ignat, Tiberius; Ayris, Paul; Gini, Beatrice; Stepankova, Olga; Özdemir, Deniz; Bal, Damla; Deyanova, Yordanka

Impact of concurrent genomic alterations in epidermal growth factor receptor (EGFR)-mutated lung cancer

表皮生长因子受体 (EGFR) 突变型肺癌中并发基因组改变的影响

Gini, Beatrice; Thomas, Nicholas; Blakely, Collin M

Saccharomyces jurei sp. nov., isolation and genetic identification of a novel yeast species from Quercus robur

Saccharomyces jurei sp. nov.,从欧洲栎(Quercus robur)中分离和遗传鉴定出一种新的酵母菌种。

Naseeb, Samina; James, Stephen A; Alsammar, Haya; Michaels, Christopher J; Gini, Beatrice; Nueno-Palop, Carmen; Bond, Christopher J; McGhie, Henry; Roberts, Ian N; Delneri, Daniela

Single-Cell Phosphoproteomics Resolves Adaptive Signaling Dynamics and Informs Targeted Combination Therapy in Glioblastoma

单细胞磷酸化蛋白质组学解析胶质母细胞瘤的适应性信号传导动力学,并为靶向联合治疗提供信息

Wei, Wei; Shin, Young Shik; Xue, Min; Matsutani, Tomoo; Masui, Kenta; Yang, Huijun; Ikegami, Shiro; Gu, Yuchao; Herrmann, Ken; Johnson, Dazy; Ding, Xiangming; Hwang, Kiwook; Kim, Jungwoo; Zhou, Jian; Su, Yapeng; Li, Xinmin; Bonetti, Bruno; Chopra, Rajesh; James, C David; Cavenee, Webster K; Cloughesy, Timothy F; Mischel, Paul S; Heath, James R; Gini, Beatrice

Genetic variation in offspring indirectly influences the quality of maternal behaviour in mice

后代的遗传变异间接影响小鼠的母性行为质量。

Ashbrook, David George; Gini, Beatrice; Hager, Reinmar

Greater than the sum of its parts: single-nucleus sequencing identifies convergent evolution of independent EGFR mutants in GBM

单核测序揭示胶质母细胞瘤中独立EGFR突变体的趋同进化,其整体效应大于各部分之和。

Gini, Beatrice; Mischel, Paul S

EGFR mutation-induced alternative splicing of Max contributes to growth of glycolytic tumors in brain cancer.

EGFR 突变诱导的 Max 选择性剪接促进脑癌中糖酵解肿瘤的生长

Babic Ivan, Anderson Erik S, Tanaka Kazuhiro, Guo Deliang, Masui Kenta, Li Bing, Zhu Shaojun, Gu Yuchao, Villa Genaro R, Akhavan David, Nathanson David, Gini Beatrice, Mareninov Sergey, Li Rui, Camacho Carolina Espindola, Kurdistani Siavash K, Eskin Ascia, Nelson Stanley F, Yong William H, Cavenee Webster K, Cloughesy Timothy F, Christofk Heather R, Black Douglas L, Mischel Paul S

mTOR complex 2 controls glycolytic metabolism in glioblastoma through FoxO acetylation and upregulation of c-Myc.

mTOR 复合物 2 通过 FoxO 乙酰化和 c-Myc 上调控制胶质母细胞瘤中的糖酵解代谢

Masui Kenta, Tanaka Kazuhiro, Akhavan David, Babic Ivan, Gini Beatrice, Matsutani Tomoo, Iwanami Akio, Liu Feng, Villa Genaro R, Gu Yuchao, Campos Carl, Zhu Shaojun, Yang Huijun, Yong William H, Cloughesy Timothy F, Mellinghoff Ingo K, Cavenee Webster K, Shaw Reuben J, Mischel Paul S