日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Discovery of cell active macrocyclic peptides with on-target inhibition of KRAS signaling

发现具有靶向抑制KRAS信号通路活性的细胞活性大环肽

Lim, Shuhui; Boyer, Nicolas; Boo, Nicole; Huang, Chunhui; Venkatachalam, Gireedhar; Angela Juang, Yu-Chi; Garrigou, Michael; Kaan, Hung Yi Kristal; Duggal, Ruchia; Peh, Khong Ming; Sadruddin, Ahmad; Gopal, Pooja; Yuen, Tsz Ying; Ng, Simon; Kannan, Srinivasaraghavan; Brown, Christopher J; Verma, Chandra S; Orth, Peter; Peier, Andrea; Ge, Lan; Yu, Xiang; Bhatt, Bhavana; Chen, Feifei; Wang, Erjia; Li, Nianyu Jason; Gonzales, Raymond J; Stoeck, Alexander; Henry, Brian; Sawyer, Tomi K; Lane, David P; Johannes, Charles W; Biswas, Kaustav; Partridge, Anthony W

Rapid Evaluation of Small Molecule Cellular Target Engagement with a Luminescent Thermal Shift Assay

利用发光热位移法快速评估小分子与细胞靶标的结合

Mortison, Jonathan D; Cornella-Taracido, Ivan; Venkatchalam, Gireedhar; Partridge, Anthony W; Siriwardana, Nirodhini; Bushell, Simon M

Replication stress-induced endogenous DNA damage drives cellular senescence induced by a sub-lethal oxidative stress

复制应激诱导的内源性 DNA 损伤导致亚致死氧化应激诱导的细胞衰老

Gireedhar Venkatachalam, Uttam Surana, Marie-Véronique Clément

Sub-lethal oxidative stress induces lysosome biogenesis via a lysosomal membrane permeabilization-cathepsin-caspase 3-transcription factor EB-dependent pathway

亚致死氧化应激通过溶酶体膜通透性-组织蛋白酶-胱天蛋白酶 3-转录因子 EB 依赖途径诱导溶酶体生物合成

San Min Leow, Shu Xian Serene Chua, Gireedhar Venkatachalam, Liang Shen, Le Luo, Marie-Veronique Clement

Computational identification and experimental validation of PPRE motifs in NHE1 and MnSOD genes of human

人类 NHE1 和 MnSOD 基因中 PPRE 基序的计算识别和实验验证

Gireedhar Venkatachalam, Alan Prem Kumar, Loo Ser Yue, Shazib Pervaiz, Marie Veronique Clement, Meena Kishore Sakharkar