日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

89 Integrated fetal testicular transcriptomic and epigenomic profiles during maternal nutrient restriction with dietary melatonin intervention

89. 母体营养限制联合膳食褪黑素干预期间胎儿睾丸转录组和表观基因组的整合分析

Lin, Steven H; Wang, Jing; Saintigny, Pierre; Wu, Chia-Chin; Giri, Uma; Zhang, Jing; Menju, Toshi; Diao, Lixia; Byers, Lauren; Weinstein, John N; Coombes, Kevin R; Girard, Luc; Komaki, Ritsuko; Wistuba, Ignacio I; Date, Hiroshi; Minna, John D; Heymach, John V; Leung, Yuk Yee; Kuksa, Pavel P; Cifello, Jeffrey; Greenfest‐Allen, Emily; Boateng, Louisa; Laub, Shannon; Tulina, Natalia; Schellenberg, Gerard D; Chesi, Alessandra; Wang, Li‐San; Chang, Chia-Hsuan; Huang, Kuang-Ta; Lee, Chien-Nan; Chu, Kuan-Yu; Shen, Yu-Li; Wang, Bei-Wen; Ku, Wei-Chi; Huang, Rwei-Fen Syu; shen, Angeline; Wang, Paul; De Sousa, Sunita M C; Torpy, David J; Scott, Hamish; King, James; Colman, Peter Grahame; Yates, Christopher James; Daous, Hala El; Contreras-Correa, Zully; Lemley, Caleb O; Rajput, Shiveeli; Sidelinger, Darcie R; King, Heath H; Arick, Mark A; Littlejohn, Brittni P

Population-level comparisons of gene regulatory networks modeled on high-throughput single-cell transcriptomics data

基于高通量单细胞转录组学数据构建的基因调控网络群体水平比较

Osorio, Daniel; Capasso, Anna; Eckhardt, S Gail; Giri, Uma; Somma, Alexander; Pitts, Todd M; Lieu, Christopher H; Messersmith, Wells A; Bagby, Stacey M; Singh, Harinder; Das, Jishnu; Sahni, Nidhi; Yi, S Stephen; Kuijjer, Marieke L

The HGF/c-MET Pathway Is a Driver and Biomarker of VEGFR-inhibitor Resistance and Vascular Remodeling in Non-Small Cell Lung Cancer

HGF/c-MET通路是VEGFR抑制剂耐药性和非小细胞肺癌血管重塑的驱动因素和生物标志物

Cascone, Tina; Xu, Li; Lin, Heather Y; Liu, Wenbin; Tran, Hai T; Liu, Yuan; Howells, Kathryn; Haddad, Vincent; Hanrahan, Emer; Nilsson, Monique B; Cortez, Maria A; Giri, Uma; Kadara, Humam; Saigal, Babita; Park, Yun-Yong; Peng, Weiyi; Lee, Ju-Seog; Ryan, Anderson J; Jüergensmeier, Juliane M; Herbst, Roy S; Wang, Jing; Langley, Robert R; Wistuba, Ignacio I; Lee, Jack J; Heymach, John V

Co-occurring genomic alterations define major subsets of KRAS-mutant lung adenocarcinoma with distinct biology, immune profiles, and therapeutic vulnerabilities.

共存的基因组改变定义了 KRAS 突变肺腺癌的主要亚型,这些亚型具有不同的生物学特性、免疫特征和治疗脆弱性

Skoulidis Ferdinandos, Byers Lauren A, Diao Lixia, Papadimitrakopoulou Vassiliki A, Tong Pan, Izzo Julie, Behrens Carmen, Kadara Humam, Parra Edwin R, Canales Jaime Rodriguez, Zhang Jianjun, Giri Uma, Gudikote Jayanthi, Cortez Maria A, Yang Chao, Fan Youhong, Peyton Michael, Girard Luc, Coombes Kevin R, Toniatti Carlo, Heffernan Timothy P, Choi Murim, Frampton Garrett M, Miller Vincent, Weinstein John N, Herbst Roy S, Wong Kwok-Kin, Zhang Jianhua, Sharma Padmanee, Mills Gordon B, Hong Waun K, Minna John D, Allison James P, Futreal Andrew, Wang Jing, Wistuba Ignacio I, Heymach John V

A high content clonogenic survival drug screen identifies mek inhibitors as potent radiation sensitizers for KRAS mutant non-small-cell lung cancer.

高含量克隆形成存活药物筛选发现,MEK 抑制剂是 KRAS 突变型非小细胞肺癌的有效放射增敏剂

Lin Steven H, Zhang Jing, Giri Uma, Stephan Clifford, Sobieski Mary, Zhong Ling, Mason Kathy A, Molkentine Jessica, Thames Howard D, Yoo Stephen S, Heymach John V

Proteomic profiling identifies dysregulated pathways in small cell lung cancer and novel therapeutic targets including PARP1

蛋白质组学分析揭示了小细胞肺癌中失调的通路以及包括PARP1在内的新型治疗靶点。

Byers, Lauren Averett; Wang, Jing; Nilsson, Monique B; Fujimoto, Junya; Saintigny, Pierre; Yordy, John; Giri, Uma; Peyton, Michael; Fan, You Hong; Diao, Lixia; Masrorpour, Fatemeh; Shen, Li; Liu, Wenbin; Duchemann, Boris; Tumula, Praveen; Bhardwaj, Vikas; Welsh, James; Weber, Stephanie; Glisson, Bonnie S; Kalhor, Neda; Wistuba, Ignacio I; Girard, Luc; Lippman, Scott M; Mills, Gordon B; Coombes, Kevin R; Weinstein, John N; Minna, John D; Heymach, John V

TP53 disruptive mutations lead to head and neck cancer treatment failure through inhibition of radiation-induced senescence

TP53破坏性突变通过抑制辐射诱导的衰老导致头颈癌治疗失败

Skinner, Heath D; Sandulache, Vlad C; Ow, Thomas J; Meyn, Raymond E; Yordy, John S; Beadle, Beth M; Fitzgerald, Alison L; Giri, Uma; Ang, K Kian; Myers, Jeffrey N

DNA repair biomarker profiling of head and neck cancer: Ku80 expression predicts locoregional failure and death following radiotherapy

头颈癌的 DNA 修复生物标志物分析:Ku80 表达可预测放射治疗后的局部区域失败和死亡

Benjamin J Moeller, John S Yordy, Michelle D Williams, Uma Giri, Uma Raju, David P Molkentine, Lauren A Byers, John V Heymach, Michael D Story, J Jack Lee, Erich M Sturgis, Randal S Weber, Adam S Garden, K Kian Ang, David L Schwartz

Blasted cell line names

爆破细胞系名称

Wang, Jing; Byers, Lauren A; Yordy, John S; Liu, Wenbin; Shen, Li; Baggerly, Keith A; Giri, Uma; Myers, Jeffrey N; Ang, K Kian; Story, Michael D; Girard, Luc; Minna, John D; Heymach, John V; Coombes, Kevin R

miRNA expression profiles in head and neck squamous cell carcinoma and adjacent normal tissue

头颈部鳞状细胞癌及其邻近正常组织中miRNA表达谱

Ramdas, Latha; Giri, Uma; Ashorn, Cheryl L; Coombes, Kevin R; El-Naggar, Adel; Ang, K Kian; Story, Michael D