日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Correction: Chronic administration of Metformin exerts cytostatic and cytotoxic effects via the PP2A-GSK3β-MCL-1 pathway by inhibiting the tmCLIC1 membrane protein in glioblastoma-initiating cells

更正：长期服用二甲双胍可通过抑制胶质母细胞瘤起始细胞中的 tmCLIC1 膜蛋白，经由 PP2A-GSK3β-MCL-1 通路发挥细胞抑制和细胞毒性作用。

期刊:Journal of Experimental & Clinical Cancer Research
影响因子:12.8
doi:10.1186/s13046-025-03628-9
Cianci, Francesca; Verduci, Ivan; Cazzoli, Riccardo; Cannavale, Gaetano; Rey, Guido; Veronesi, Marina; Balboni, Beatrice; Ranucci, Matteo; Palloni, Luca Maria Giovanni; Ballabio, Federico; Barsotti, Noemi; Ailuno, Giorgia; Balboni, Alice; Baldassari, Sara; Caviglioli, Gabriele; Tacconi, Carlotta; Camilloni, Carlo; Girotto, Stefania; Fantin, Alessandro; Barbieri, Federica; Cavalli, Andrea; Pasqualetti, Massimo; Florio, Tullio; Minucci, Saverio; Mazzanti, Michele
信号转导
细胞生物学
毒理研究
GSK3
发表日期：2026
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A Metabolites' Interplay Can Modulate DNA Repair by Homologous Recombination.

代谢物的相互作用可通过同源重组调节DNA修复。

期刊:International Journal of Molecular Sciences
影响因子:4.9
doi:10.3390/ijms27031517
Rossi Valentina, Masi Mirco, Govoni Marzia, Veronesi Marina, Duca Martina, Girotto Stefania, Cavalli Andrea, Di Stefano Giuseppina
代谢
发表日期：2026
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Targeting RAD51-BRCA2 Interaction to Enhance Synthetic Lethality with Olaparib in Pancreatic Cancer: Development of a Novel Phenyl Furan-Quinoline-Carboxylic Acid Series

靶向 RAD51-BRCA2 相互作用以增强奥拉帕尼在胰腺癌中的合成致死性：新型苯基呋喃-喹啉-羧酸系列化合物的开发

期刊:ACS Medicinal Chemistry Letters
影响因子:4
doi:10.1021/acsmedchemlett.5c00711
Ferrandi, Giovanni; Bagnolini, Greta; Poppi, Laura; Masi, Mirco; Previtali, Viola; Andonaia, Angela; Varignani, Giulia; Veronesi, Marina; De Franco, Francesca; Falchi, Federico; Di Stefano, Giuseppina; Girotto, Stefania; Roberti, Marinella; Cavalli, Andrea
肿瘤
肿瘤免疫
BRCA2
RAD51
胰腺癌
发表日期：2026
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New allosteric modulators of molecular chaperone TRAP1 from the integration of computational biology, medicinal chemistry, and biophysics

结合计算生物学、药物化学和生物物理学，发现分子伴侣TRAP1的新型变构调节剂

期刊:Cell Stress & Chaperones
影响因子:3.2
doi:10.1016/j.cstres.2026.100162
Guarra, Federica; Komarov, Denis; Ciamarone, Andrea; Torielli, Luca; Previtali, Viola; Margaroli, Natasha; Romeo, Elisa; La Spina, Martina; Sbuelz, Francesca; Laquatra, Claudio; Veronesi, Marina; Lolicato, Marco; Arrigoni, Cristina; Moroni, Elisabetta; Serapian, Stefano A; Girotto, Stefania; Rasola, Andrea; Colombo, Giorgio
TRAP1
发表日期：2026
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Computationally-designed aptamers targeting RAD51-BRCA2 interaction impair homologous recombination and induce synthetic lethality

针对 RAD51-BRCA2 相互作用的计算机设计适体可损害同源重组并诱导合成致死性

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-025-66694-9
Milordini, Giulia; Zacco, Elsa; Masi, Mirco; Armaos, Alexandros; Di Palma, Francesco; Oneto, Michele; Gilodi, Martina; Rupert, Jakob; Broglia, Laura; Varignani, Giulia; Scotto, Marco; Marotta, Roberto; Girotto, Stefania; Cavalli, Andrea; Tartaglia, Gian Gaetano
BRCA2
RAD51
发表日期：2025
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Chronic administration of metformin exerts cytostatic and cytotoxic effects via the PP2A-GSK3β-MCL-1 pathway by inhibiting the tmCLIC1 membrane protein in glioblastoma-initiating cells

长期服用二甲双胍可通过抑制胶质母细胞瘤起始细胞中的tmCLIC1膜蛋白，经由PP2A-GSK3β-MCL-1通路发挥细胞抑制和细胞毒性作用。

期刊:Journal of Experimental & Clinical Cancer Research
影响因子:12.8
doi:10.1186/s13046-025-03577-3
Cianci, Francesca; Verduci, Ivan; Cazzoli, Riccardo; Cannavale, Gaetano; Rey, Guido; Veronesi, Marina; Balboni, Beatrice; Ranucci, Matteo; Palloni, Luca Maria Giovanni; Ballabio, Federico; Barsotti, Noemi; Ailuno, Giorgia; Balboni, Alice; Baldassari, Sara; Caviglioli, Gabriele; Tacconi, Carlotta; Camilloni, Carlo; Girotto, Stefania; Barbieri, Federica; Fantin, Alessandro; Cavalli, Andrea; Pasqualetti, Massimo; Florio, Tullio; Minucci, Saverio; Mazzanti, Michele
信号转导
细胞生物学
毒理研究
GSK3
发表日期：2025
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Dissecting the RAD51-BRC4 Interaction Landscape through Integrative Molecular Simulations and Experimental Biophysics

通过整合分子模拟和实验生物物理学方法剖析 RAD51-BRC4 相互作用图谱

期刊:Journal of Chemical Information and Modeling
影响因子:5.3
doi:10.1021/acs.jcim.5c01639
Bresciani, Veronica; Rinaldi, Francesco; Franco, Pedro; Girotto, Stefania; Cavalli, Andrea; Langer, Julian D; Masetti, Matteo; Bernetti, Mattia
RAD51
发表日期：2025
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GSK-3β Allosteric Inhibition: A Dead End or a New Pharmacological Frontier?

GSK-3β变构抑制：是死胡同还是新的药理学前沿？

期刊:International Journal of Molecular Sciences
影响因子:4.9
doi:10.3390/ijms24087541
Balboni, Beatrice; Masi, Mirco; Rocchia, Walter; Girotto, Stefania; Cavalli, Andrea
发表日期：2023
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Novel Insights into RAD52's Structure, Function, and Druggability for Synthetic Lethality and Innovative Anticancer Therapies

RAD52的结构、功能和成药性方面的新见解及其在合成致死和创新抗癌疗法中的应用

期刊:Cancers
影响因子:4.4
doi:10.3390/cancers15061817
Balboni, Beatrice; Rinaldi, Francesco; Previtali, Viola; Ciamarone, Andrea; Girotto, Stefania; Cavalli, Andrea
肿瘤
RAD52
肿瘤免疫
发表日期：2023
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Identification of Novel GSK-3β Hits Using Competitive Biophysical Assays.

利用竞争性生物物理测定法鉴定新型 GSK-3β 先导化合物

期刊:International Journal of Molecular Sciences
影响因子:4.9
doi:10.3390/ijms23073856
Balboni Beatrice, Tripathi Shailesh Kumar, Veronesi Marina, Russo Debora, Penna Ilaria, Giabbai Barbara, Bandiera Tiziano, Storici Paola, Girotto Stefania, Cavalli Andrea
其它
发表日期：2022
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