The CD64/CD28/CD3ζ chimeric receptor reprograms T-cell metabolism and promotes T-cell persistence and immune functions while triggering antibody-independent and antibody-dependent cytotoxicity
CD64/CD28/CD3ζ嵌合受体可重编程T细胞代谢，促进T细胞持久性和免疫功能，同时触发抗体非依赖性和抗体依赖性细胞毒性。
期刊:Experimental Hematology & Oncology
影响因子:9.4
doi:10.1186/s40164-025-00601-2.
Sara Caratelli,Francesca De Paolis,Domenico Alessandro Silvestris,Silvia Baldari,Illari Salvatori,Apollonia Tullo,Giulia Lanzilli,Aymone Gurtner,Alberto Ferri,Cristiana Valle,Simona Padovani,Valeriana Cesarini,Tommaso Sconocchia,Loredana Cifaldi,Roberto Arriga,Giulio Cesare Spagnoli,Soldano Ferrone,Adriano Venditti,Piero Rossi,Graziano Pesole,Gabriele Toietta,Giuseppe Sconocchia
细胞生物学
代谢
毒理研究
免疫/内分泌
T细胞
CD28
CD2
CD3
CD6
CD64
T细胞
