An engineered chimeric toxin that cleaves activated mutant and wild-type RAS inhibits tumor growth
一种经基因工程改造的嵌合毒素,能够切割活化的突变型和野生型RAS蛋白,从而抑制肿瘤生长。
期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.2000312117
Vidimar, Vania; Beilhartz, Greg L; Park, Minyoung; Biancucci, Marco; Kieffer, Matthew B; Gius, David R; Melnyk, Roman A; Satchell, Karla J F