日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Biomarkers of Drug-Induced Kidney Injury: Use in Clinical Trials and Recent Examples of Impact on Drug Development

药物性肾损伤的生物标志物:在临床试验中的应用及对药物研发影响的最新实例

Zabka, Tanja S; Lawton, Michael; Chu, Tom; Friedman, Gary S; Peron, Katrina; Sultana, Stefan R; Glaab, Warren E; King, Nicholas M P

LINE-1 transposition into murine Thyroglobulin results in congenital thyroid dysplasia.

LINE-1 转座到小鼠甲状腺球蛋白中会导致先天性甲状腺发育不良

Bailey Wendy J, Smits Bart M G, Erdos Zoltan, Gaspar John M, Lane Pamela, Kuruvilla Sabu, Rosahl Thomas W, Thudium Douglas, Wang Jingzhou, Glaab Warren E, MacGowan Melissa, Multari Heather, Cumo Christine, Navis Adam, Forest Thomas

A mechanistic biomarker investigation of fialuridine hepatotoxicity using the chimeric TK-NOG Hu-liver mouse model and in vitro micropatterned hepatocyte cocultures

利用嵌合TK-NOG Hu-liver小鼠模型和体外微图案化肝细胞共培养技术,对非拉尿苷肝毒性进行机制生物标志物研究

Aslamkhan, Amy G; Michna, Laura; Podtelezhnikov, Alexei; Vlasakova, Katerina; Suemizu, Hiroshi; Ohnishi, Yasuyuki; Liu, Liping; Lane, Pamela; Xu, Qiuwei; Kuhls, Matthew C; Wang, Zhibin; Pacchione, Stephen; Erdos, Zoltan; Tracy, Rodger William; Koeplinger, Kenneth; Muniappa, Nagaraja; Valentine, John; Galijatovic-Idrizbegovic, Alema; Glaab, Warren E; Sistare, Frank D; Lebron, Jose

Systems analysis of miRNA biomarkers to inform drug safety

利用miRNA生物标志物进行系统分析以指导药物安全性

Schofield, Amy L; Brown, Joseph P; Brown, Jack; Wilczynska, Ania; Bell, Catherine; Glaab, Warren E; Hackl, Matthias; Howell, Lawrence; Lee, Stephen; Dear, James W; Remes, Mika; Reeves, Paul; Zhang, Eunice; Allmer, Jens; Norris, Alan; Falciani, Francesco; Takeshita, Louise Y; Seyed Forootan, Shiva; Sutton, Robert; Park, B Kevin; Goldring, Chris

Net Reclassification Index and Integrated Discrimination Index Are Not Appropriate for Testing Whether a Biomarker Improves Predictive Performance

净重分类指数和综合判别指数不适用于检验生物标志物是否能提高预测性能。

Burch, Peter M; Glaab, Warren E; Holder, Daniel J; Phillips, Jonathan A; Sauer, John-Michael; Walker, Elizabeth G

A rapid urine test for early detection of kidney injury

一种用于早期发现肾损伤的快速尿液检测方法

Vaidya, Vishal S; Ford, Glen M; Waikar, Sushrut S; Wang, Yizhuo; Clement, Matthew B; Ramirez, Victoria; Glaab, Warren E; Troth, Sean P; Sistare, Frank D; Prozialeck, Walter C; Edwards, Joshua R; Bobadilla, Norma A; Mefferd, Stephen C; Bonventre, Joseph V