日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Cleavage and activation of the severe acute respiratory syndrome coronavirus spike protein by human airway trypsin-like protease

人呼吸道胰蛋白酶样蛋白酶对严重急性呼吸综合征冠状病毒刺突蛋白的切割和激活

Bertram, Stephanie; Glowacka, Ilona; Müller, Marcel A; Lavender, Hayley; Gnirss, Kerstin; Nehlmeier, Inga; Niemeyer, Daniela; He, Yuxian; Simmons, Graham; Drosten, Christian; Soilleux, Elizabeth J; Jahn, Olaf; Steffen, Imke; Pöhlmann, Stefan

Evidence that TMPRSS2 activates the severe acute respiratory syndrome coronavirus spike protein for membrane fusion and reduces viral control by the humoral immune response.

有证据表明,TMPRSS2 可激活严重急性呼吸综合征冠状病毒的刺突蛋白,使其发生膜融合,从而降低体液免疫反应对病毒的控制作用

Glowacka Ilona, Bertram Stephanie, Müller Marcel A, Allen Paul, Soilleux Elizabeth, Pfefferle Susanne, Steffen Imke, Tsegaye Theodros Solomon, He Yuxian, Gnirss Kerstin, Niemeyer Daniela, Schneider Heike, Drosten Christian, Pöhlmann Stefan