日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Perspective on LC-MS(/MS) for biotherapeutic and biomarker proteins in research and regulated Bioanalysis: a consolidation of more than a decade of experience across the European Bioanalysis Forum community (Part 2: "The How")

关于液相色谱-质谱联用(/质谱)在生物治疗和生物标志物蛋白研究及监管生物分析中的应用展望：欧洲生物分析论坛社群十余年经验的总结（第二部分：“方法”）

期刊:Bioanalysis
影响因子:1.8
doi:10.1080/17576180.2024.2418251
de Merbel, Nico van; Gnoth, Mark Jean; Wilson, Amanda; Blattmann, Peter; Ingelse, Benno; Jordan, Gregor; Fusetti, Fabrizia; Blackburn, Michael; Sporring, Sune Hove; Love, Iain; Muccio, Stephane; Barfield, Matthew; Wheller, Rob; Timmerman, Philip
发表日期：2025
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Perspective on LC-MS(/MS) for biotherapeutic and biomarker proteins in research and regulated Bioanalysis: a consolidation of more than a decade of experience across the European Bioanalysis Forum community (Part 1: "The What")

关于液相色谱-质谱联用(LC-MS/MS)在生物治疗和生物标志物蛋白研究及监管生物分析中的应用展望：欧洲生物分析论坛社群十余年经验的总结（第一部分：“是什么”）

期刊:Bioanalysis
影响因子:1.8
doi:10.1080/17576180.2024.2418250
Wilson, Amanda; Gnoth, Mark Jean; de Merbel, Nico van; Blattmann, Peter; Ingelse, Benno; Jordan, Gregor; Fusetti, Fabrizia; Blackburn, Michael; Sporring, Sune Hove; Love, Iain; Muccio, Stephane; Barfield, Matthew; Wheller, Rob; Timmerman, Philip
多发性硬化症
发表日期：2025
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Identification of isoAsp7-Aβ as a major Aβ variant in Alzheimer's disease, dementia with Lewy bodies and vascular dementia

鉴定出isoAsp7-Aβ是阿尔茨海默病、路易体痴呆和血管性痴呆中的主要Aβ变体

期刊:Acta Neuropathologica
影响因子:9.3
doi:10.1007/s00401-024-02824-9
Schrempel, Sarah; Kottwitz, Anna Katharina; Piechotta, Anke; Gnoth, Kathrin; Büschgens, Luca; Hartlage-Rübsamen, Maike; Morawski, Markus; Schenk, Mathias; Kleinschmidt, Martin; Serrano, Geidy E; Beach, Thomas G; Rostagno, Agueda; Ghiso, Jorge; Heneka, Michael T; Walter, Jochen; Wirths, Oliver; Schilling, Stephan; Roßner, Steffen
阿尔茨海默症
发表日期：2024
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Contribution of amino acids in the active site of dipeptidyl peptidase 4 to the catalytic action of the enzyme

二肽基肽酶4活性位点氨基酸对酶催化作用的贡献

期刊:PLoS One
影响因子:2.9
doi:10.1371/journal.pone.0289239
Kathrin Gnoth, Joachim Wolfgang Bär, Fred Rosche, Jens-Ulrich Rahfeld, Hans-Ulrich Demuth
发表日期：2024
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The use of surrogate matrices in bioanalytical preclinical safety testing using chromatographic methods: a recommendation from the European Bioanalysis forum

欧洲生物分析论坛关于在采用色谱法进行生物分析临床前安全性测试中使用替代基质的建议

期刊:Bioanalysis
影响因子:1.8
doi:10.1080/17576180.2024.2416360
Goodwin, Lee; McDougall, Stuart; Gnoth, Mark Jean; Mascher, Daniel; Ferrari, Luca; Wheller, Robert; Hawthorne, Hayley; Jansat, Josep-Maria; Faber, Joerg; Huber, Peter; Greco, Alessandro; Eggers, Lars F; Sury, Matthias; Karlsson, Jens-Jakob; Sporring, Sune Hove; Globig, Susanne; van de Merbel, Nico; Timmerman, Philip
发表日期：2024
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Seeding, maturation and propagation of amyloid β-peptide aggregates in Alzheimer's disease

阿尔茨海默病中淀粉样β肽聚集体的接种、成熟和增殖

期刊:Brain
影响因子:10.6
doi:10.1093/brain/awac202
Xiaohang Li, Simona Ospitalieri, Tessa Robberechts, Linda Hofmann, Christina Schmid, Ajeet Rijal Upadhaya, Marta J Koper, Christine A F von Arnim, Sathish Kumar, Michael Willem, Kathrin Gnoth, Meine Ramakers, Joost Schymkowitz, Frederic Rousseau, Jochen Walter, Alicja Ronisz, Karthikeyan Balakrishna
神经
阿尔茨海默症
发表日期：2022
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Evidence for Enhanced Efficacy of Passive Immunotherapy against Beta-Amyloid in CD33-Negative 5xFAD Mice

CD33阴性5xFAD小鼠被动免疫疗法对β-淀粉样蛋白疗效增强的证据

期刊:Biomolecules
影响因子:
doi:10.3390/biom12030399
Gnoth, Kathrin; Geissler, Stefanie; Feldhaus, Julia; Taudte, Nadine; Ilse, Victoria; Zürner, Sebastian; Greiser, Sebastian; Braumann, Ulf-Dietrich; Rahfeld, Jens-Ulrich; Cynis, Holger; Schilling, Stephan
CD3
CD33
免疫/内分泌
发表日期：2022
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The phospholipase D inhibitor FIPI potently blocks EGF-induced calcium signaling in human breast cancer cells

磷脂酶 D 抑制剂 FIPI 可有效阻断人类乳腺癌细胞中 EGF 诱导的钙信号传导

期刊:Cell Communication and Signaling
影响因子:8.2
doi:10.1186/s12964-021-00724-z
Helena M Stricker, Nadine Rommerswinkel, Silvia Keil, Sandina A Gnoth, Bernd Niggemann, Thomas Dittmar
信号转导
肿瘤
乳腺癌
肿瘤细胞
GPCR/Calcium/cAMP
Human
发表日期：2021
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The protein architecture of the endocytic coat analyzed by FRET microscopy

通过 FRET 显微镜分析内吞外壳的蛋白质结构

期刊:Molecular Systems Biology
影响因子:8.5
doi:10.15252/msb.20199009
Michal Skruzny, Emma Pohl, Sandina Gnoth, Gabriele Malengo, Victor Sourjik
RET
发表日期：2020
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Targeting isoaspartate-modified Aβ rescues behavioral deficits in transgenic mice with Alzheimer's disease-like pathology

靶向异天冬氨酸修饰的 Aβ 可挽救患有阿尔茨海默病样病理的转基因小鼠的行为缺陷

期刊:Alzheimers Research & Therapy
影响因子:7.9
doi:10.1186/s13195-020-00719-x
Kathrin Gnoth, Anke Piechotta, Martin Kleinschmidt, Sandra Konrath, Mathias Schenk, Nadine Taudte, Daniel Ramsbeck, Vera Rieckmann, Stefanie Geissler, Rico Eichentopf, Susan Barendrecht, Maike Hartlage-Rübsamen, Hans-Ulrich Demuth, Steffen Roßner, Holger Cynis, Jens-Ulrich Rahfeld, Stephan Schilling
神经
阿尔茨海默症
发表日期：2020
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