日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Structure and Interactions of HIV-1 gp41 CHR-NHR Reverse Hairpin Constructs Reveal Molecular Determinants of Antiviral Activity

HIV-1 gp41 CHR-NHR 反向发夹结构的结构和相互作用揭示了抗病毒活性的分子决定因素

He, Li; McAndrew, Ryan; Barbu, Razvan; Gifford, Grant; Halacoglu, Cari; Drouin-Allaire, Camille; Weber, Lindsey; Kristensen, Line G; Gupta, Sayan; Chen, Yan; Petzold, Christopher J; Allaire, Marc; Li, Kathy H; Ralston, Corie Y; Gochin, Miriam

Correction: Reduced miR-200b and miR-200c expression contributes to abnormal hepatic lipid accumulation by stimulating JUN expression and activating the transcription of srebp1

更正:miR-200b 和 miR-200c 表达降低通过刺激 JUN 表达和激活 srebp1 转录,导致肝脏脂质异常积累。

Cai, Lifeng; Gochin, Miriam; Liu, Keliang; Guo, Jun; Fang, Weiwei; Sun, Libo; Lu, Yonggang; Dou, Lin; Huang, Xiuqing; Sun, Mingxiao; Pang, Cheng; Qu, Jing; Liu, Guanghui; Li, Jian

A targeted covalent small molecule inhibitor of HIV-1 fusion

一种靶向HIV-1融合的共价小分子抑制剂

Zhou, Guangyan; He, Li; Li, Kathy H; Pedroso, Cássio C S; Gochin, Miriam

Biophysical studies of HIV-1 glycoprotein-41 interactions with peptides and small molecules - Effect of lipids and detergents

HIV-1糖蛋白-41与肽和小分子相互作用的生物物理学研究——脂质和去垢剂的影响

Zhou, Guangyan; Chu, Shidong; Kohli, Aditya; Szoka, Francis C; Gochin, Miriam

Investigation of the molecular characteristics of bisindole inhibitors as HIV-1 glycoprotein-41 fusion inhibitors

对双吲哚抑制剂作为HIV-1糖蛋白-41融合抑制剂的分子特性进行研究

Zhou, Guangyan; Chu, Shidong; Nemati, Ariana; Huang, Chunsheng; Snyder, Beth A; Ptak, Roger G; Gochin, Miriam

Enhanced potency of bivalent small molecule gp41 inhibitors

双价小分子 gp41 抑制剂的增强效力

Vladimir Sofiyev, Hardeep Kaur, Beth A Snyder, Priscilla A Hogan, Roger G Ptak, Peter Hwang, Miriam Gochin

Swapped-domain constructs of the glycoprotein-41 ectodomain are potent inhibitors of HIV infection

糖蛋白-41 胞外域的交换结构域构建体是 HIV 感染的强效抑制剂

Shidong Chu, Hardeep Kaur, Ariana Nemati, Joseph D Walsh, Vivian Partida, Shao-Qing Zhang, Miriam Gochin

Design and characterization of swapped-domain constructs of HIV-1 glycoprotein-41 as receptors for drug discovery

HIV-1 糖蛋白-41 交换结构域构建体的设计和表征作为药物发现受体

Joseph D Walsh, Shidong Chu, Shao-Qing Zhang, Miriam Gochin

Small molecule inhibitors of HIVgp41 N-heptad repeat trimer formation

HIVgp41 N-七肽重复序列三聚体形成的小分子抑制剂

Allen, William J; Yi, Hyun Ah; Gochin, Miriam; Jacobs, Amy; Rizzo, Robert C

Strategies for lead discovery: application of footprint similarity targeting HIVgp41

先导化合物发现策略:应用足迹相似性靶向 HIVgp41

Holden, Patrick M; Allen, William J; Gochin, Miriam; Rizzo, Robert C