日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Efficacy of CTLA-4 checkpoint therapy is dependent on IL-21 signaling to mediate cytotoxic reprogramming of PD-1(+)CD8(+) T cells

CTLA-4检查点疗法的疗效依赖于IL-21信号通路介导PD-1(+)CD8(+) T细胞的细胞毒性重编程。

Zhang, Zhen; Langenbach, Marlene; Sagar, Sagar; Fetsch, Viktor; Stritzker, Jonas; Severa, Elizabeth; Meng, Ke; Winkler, Frances; Rana, Nisha; Zoldan, Katharina; Godbole, Ira; Solis, Sabrina; Weber, Jeffrey S; Rafei-Shamsabadi, David; Lehr, Saskia; Diehl, Rebecca; Venhoff, Ana Cecilia; Voll, Reinhard E; Buettner, Nico; Neumann-Haefelin, Christoph; Boettler, Tobias; Hofmann, Maike; Boerries, Melanie; Meiss, Frank; Zeiser, Robert; Thimme, Robert; Herati, Ramin S; Bengsch, Bertram

Spatial single-cell profiling and neighbourhood analysis reveal the determinants of immune architecture connected to checkpoint inhibitor therapy outcome in hepatocellular carcinoma

空间单细胞谱分析和邻域分析揭示了与肝细胞癌检查点抑制剂治疗结果相关的免疫结构决定因素

Salié, Henrike; Wischer, Lara; D'Alessio, Antonio; Godbole, Ira; Suo, Yuan; Otto-Mora, Patricia; Beck, Juergen; Neumann, Olaf; Stenzinger, Albrecht; Schirmacher, Peter; Fulgenzi, Claudia A M; Blaumeiser, Andreas; Boerries, Melanie; Roehlen, Natascha; Schultheiß, Michael; Hofmann, Maike; Thimme, Robert; Pinato, David J; Longerich, Thomas; Bengsch, Bertram

A proteotranscriptomic approach to dissect the molecular landscape of human retinoblastoma.

利用蛋白质转录组学方法解析人类视网膜母细胞瘤的分子图谱

Wolf Julian, Hajdu Rozina Ida, Boneva Stefaniya, Godbole Ira, Stürzbecher Lucas, Auw-Haedrich Claudia, Lagrèze Wolf A, Agostini Hansjürgen, Reinhard Thomas, Tholen Stefan, Schilling Oliver, Schlunck Günther, Bengsch Bertram, Lange Clemens