日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Reference-based chemical-genetic interaction profiling to elucidate small molecule mechanism of action in Mycobacterium tuberculosis

基于参考序列的化学-遗传相互作用分析阐明结核分枝杆菌中小分子的作用机制

Bond, Austin N; Orzechowski, Marek; Zhang, Shuting; Ben-Zion, Ishay; Lemmer, Allison; Garry, Nathaniel; Lee, Katie; Chen, Michael; Delano, Kayla; Gath, Emily; Golas, A Lorelei; Nietupski, Raymond; Fitzgerald, Michael; Ehrt, Sabine; Rubin, Eric J; Sassetti, Christopher M; Schnappinger, Dirk; Shoresh, Noam; Hunt, Diana K; Gomez, James E; Hung, Deborah T

Discovery of a Pseudomonas aeruginosa-specific small molecule targeting outer membrane protein OprH-LPS interaction by a multiplexed screen.

通过多重筛选发现了一种靶向铜绿假单胞菌外膜蛋白 OprH-LPS 相互作用的小分子

Poulsen Bradley E, Warrier Thulasi, Barkho Sulyman, Bagnall Josephine, Romano Keith P, White Tiantian, Yu Xiao, Kawate Tomohiko, Nguyen Phuong H, Raines Kyra, Ferrara Kristina, Golas A Lorelei, FitzGerald Michael, Boeszoermenyi Andras, Kaushik Virendar, Serrano-Wu Michael, Shoresh Noam, Hung Deborah T