日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

APC/C-mediated ubiquitylation of extranucleosomal histone complexes lacking canonical degrons.

APC/C介导的核外组蛋白复合物泛素化,缺乏典型的降解信号

Skrajna Aleksandra, Bodrug Tatyana, Martinez-Chacin Raquel C, Fisher Caleb B, Welsh Kaeli A, Simmons Holly C, Arteaga Eyla C, Simmons Jake M, Nasr Mohamed A, LaPak Kyle M, Nguyen Anh, Huynh Mai T, Fargo Isabel, Welfare Joshua G, Zhao Yani, Lawrence David S, Goldfarb Dennis, Brown Nicholas G, McGinty Robert K

Post-translational modification of H2B C-terminal helix regulates nucleosome interactions and chromatin signaling.

H2B C 端螺旋的翻译后修饰调节核小体相互作用和染色质信号传导。

Zhao Yani, Nguyen Anh, Arteaga Eyla C, Skrajna Aleksandra, Krajewski Krzysztof, Goldfarb Dennis, McGinty Robert K

Regulation of Type 1 Diabetes via Brown Adipocyte-Secreted Proteins and the Novel Glucagon Regulator Nidogen-2.

通过棕色脂肪细胞分泌蛋白和新型胰高血糖素调节因子Nidogen-2调节1型糖尿病

Lee Jeongmin, Ustione Alessandro, Wilkerson Emily M, Balakrishnan Rekha, Thurmond Debbie C, Goldfarb Dennis, Piston David W

Inositol (1,4,5)-trisphosphate 5-phosphatase promotes survival of uveal melanoma by regulating oncogenic G protein-driven calcium oscillations

肌醇(1,4,5)-三磷酸5-磷酸酶通过调节致癌G蛋白驱动的钙振荡促进葡萄膜黑色素瘤的存活

Onken, Michael D; Makepeace, Carol M; Kaltenbronn, Kevin M; Demourelle-Washington, McKenzie; Piggott, Kisha D; Goldfarb, Dennis; Kast, David J; Jansen, Silvia; Blumer, Kendall J

The gain-of-function UBE3A(Q588E) variant causes Angelman-like neurodevelopmental phenotypes in mice.

UBE3A(Q588E) 功能获得性变异会导致小鼠出现类似安格曼综合征的神经发育表型

Weston Kellan P, Gunelson Anna M, Maloney Susan E, Ge Xia, Stelzer Jalin A, Kim Kwang-Soo, Collier Shylyn, Mindt Marissa M, Agajanian Megan J, Major Michael B, Goldfarb Dennis, Noguchi Kevin K, Yi Jason J

Proximity proteomics provides a new resource for exploring the function of Afadin and the complexity of cell-cell adherens junctions.

邻近蛋白质组学为探索 Afadin 的功能和细胞间粘附连接的复杂性提供了一种新的资源

Choi Wangsun, Goldfarb Dennis, Yan Feng, Major Michael B, Fanning Alan S, Peifer Mark

Poly-basic peptides and polymers as new drug candidates against Plasmodium falciparum.

多碱性肽和聚合物作为抗恶性疟原虫的新候选药物

Sivakumar Roshan, Floyd Katherine, Erath Jessey, Jacoby Alex, Kim Kim Jenny, Bayguinov Peter O, Fitzpatrick James A J, Goldfarb Dennis, Jovanovic Marko, Tripathi Abhai, Djuranovic Sergej, Pavlovic-Djuranovic Slavica

Insulin-Independent Regulation of Type 1 Diabetes via Brown Adipocyte-Secreted Proteins and the Novel Glucagon Regulator Nidogen-2

棕色脂肪细胞分泌蛋白和新型胰高血糖素调节因子Nidogen-2介导1型糖尿病的胰岛素非依赖性调节

Lee, Jeongmin; Ustione, Alessandro; Wilkerson, Emily M; Balakrishnan, Rekha; Thurmond, Debbie C; Goldfarb, Dennis; Piston, David W

Proximity proteomics provides a new resource for exploring the function of Afadin and the complexity of cell-cell adherens junctions

邻近蛋白质组学为探索Afadin的功能和细胞间粘附连接的复杂性提供了一种新的资源。

Choi, Wangsun; Goldfarb, Dennis; Yan, Feng; Major, M Ben; Fanning, Alan S; Peifer, Mark

Biophysical Mechanism of Allosteric Regulation of Actin Capping Protein

肌动蛋白帽状蛋白变构调节的生物物理机制

Mooren, Olivia L; Stuchell-Brereton, Melissa D; McConnell, Patrick; Yan, Chenbo; Wilkerson, Emily M; Goldfarb, Dennis; Cooper, John A; Sept, David; Soranno, Andrea