日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Mechanism-based approach in designing patient-specific combination therapies for nonsense mutation diseases

基于机制的方法设计针对无义突变疾病的患者特异性联合疗法

Bhat, Saleem Y; Bhattacharya, Arpan; Li, Hong; Cui, Xiaonan; Lueck, John D; Goldman, Yale E; Cooperman, Barry S

A myosin hypertrophic cardiomyopathy mutation disrupts the super-relaxed state and boosts contractility by enhanced actin attachment

肌球蛋白肥厚型心肌病突变会破坏超松弛状态,并通过增强肌动蛋白附着来提高收缩力。

Cail, Robert C; Barua, Bipasha; Báez-Cruz, Faviolla A; Winkelmann, Donald A; Goldman, Yale E; Ostap, E Michael

S2Tag, a novel affinity tag for the capture and immobilization of coiled-coil proteins: Application to the study of human β-cardiac myosin

S2Tag,一种用于捕获和固定卷曲螺旋蛋白的新型亲和标签:在人β-心肌肌球蛋白研究中的应用

Barua, Bipasha; Cail, Robert C; Goldman, Yale E; Ostap, E Michael; Winkelmann, Donald A

Dynamics of β-cardiac myosin between the super-relaxed and disordered-relaxed states.

β-心肌肌球蛋白在超松弛状态和无序松弛状态之间的动力学

Cail Robert C, Báez-Cruz Faviolla A, Winkelmann Donald A, Goldman Yale E, Ostap E Michael

Near-cognate tRNAs enhance tRNA rejection and prime the ribosome for rapid subsequent tRNA testing

近同源tRNA增强了tRNA的排斥作用,并使核糖体做好快速进行后续tRNA检测的准备。

Fritsch, Clark; Bhattacharya, Arpan; Ng, Martin Y; Li, Hong; Nelson, Philip C; Cooperman, Barry S; Goldman, Yale E

RNA helicases DDX3X and DDX3Y form nanometer-scale RNA-protein clusters that support catalytic activity.

RNA解旋酶DDX3X和DDX3Y形成纳米级RNA-蛋白质簇,支持催化活性

Yanas Amber, Shweta Him, Owens Michael C, Liu Kathy Fange, Goldman Yale E

DDX3X and DDX3Y constitutively form nano-sized RNA-protein clusters that foster enzymatic activity

DDX3X 和 DDX3Y 组成性地形成纳米级 RNA-蛋白质簇,从而促进酶活性。

Yanas, Amber; Shweta, Him; Owens, Michael C; Liu, Kathy Fange; Goldman, Yale E

No hype in hyperspace

超空间里没有炒作

Goldman, Yale E

Straightening Out the Elasticity of Myosin Cross-Bridges

消除肌球蛋白横桥的弹性

Linari, Marco; Piazzesi, Gabriella; Pertici, Irene; Dantzig, Jody A; Goldman, Yale E; Lombardi, Vincenzo

Processivity and Velocity for Motors Stepping on Periodic Tracks

电机在周期性轨道上运动的连续性和速度

Mugnai, Mauro L; Caporizzo, Matthew A; Goldman, Yale E; Thirumalai, D