日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Delineating Metabolic Dysfunction-Associated Steatotic Liver Disease and Comorbid Risk With Clinical, Blood and Metabolomic Parameters—A UK Biobank Analysis

利用临床、血液和代谢组学参数阐明代谢功能障碍相关脂肪肝疾病及其合并症风险——一项英国生物银行分析

Marrapu, Sudheer; Kumar, Ramesh; Bhushan, Divendu; Kumar, Sudhir; Kumar, Abhishek; Priyadarshi, Rajeev N; Anand, Utpal; Ho, Brian; Xu, Yun; Goldring, Christopher E; Goodacre, Royston; Pirmohamed, Munir

Limitations of acetaminophen as a reference hepatotoxin for the evaluation of in vitro liver models

对乙酰氨基酚作为体外肝脏模型评价的参考肝毒素的局限性

Livoti, Lucia A; Sison-Young, Rowena; Reddyhoff, Dennis; Fisher, Ciarán P; Gardner, Iain; Diaz-Nieto, Rafael; Goldring, Christopher E; Copple, Ian M

Targeting the tumor microenvironment in cholangiocarcinoma to improve immune checkpoint blockade: potential strategies and translational pre-clinical models

靶向胆管癌肿瘤微环境以增强免疫检查点阻断疗效:潜在策略和转化性临床前模型

Jessel, Maria-Danae; McGreevy, Owen; McReynolds, Lauryn; Dahal, Lekh N; Gilbert, Timothy; Malik, Hassan Z; Goldring, Christopher E; Randle, Laura E

Construction and Expression of Fc-FGF21 by Different Expression Systems and Comparison of Their Similarity and Difference with Efruxifermin by In Vitro and In Vivo Studies.

利用不同表达系统构建和表达Fc-FGF21,并通过体外和体内研究比较其与Efruxifermin的异同

Wang Xujia, Meng Qin, Jia Aijuan, Zhou Yuehua, Song Dandan, Ma Shaokang, Li Wei, Zhang Zhuobing, Goldring Christopher, Feng Hui, Wang Mu

A Preclinical Model of Human Liver Using Precision Cut Tissue Slice Culture.

利用精确切割组织切片培养技术构建人类肝脏临床前模型

McGreevy Owen, Gilbert Timothy, Jessel Maria-Danae, Bosakhar Mohammed, Fenwick Stephen, Malik Hassan, Goldring Christopher, Randle Laura

A systems approach reveals species differences in hepatic stress response capacity

系统方法揭示了不同物种在肝脏应激反应能力方面的差异

Russomanno, Giusy; Sison-Young, Rowena; Livoti, Lucia A; Coghlan, Hannah; Jenkins, Rosalind E; Kunnen, Steven J; Fisher, Ciarán P; Reddyhoff, Dennis; Gardner, Iain; Rehman, Adeeb H; Fenwick, Stephen W; Jones, Andrew R; Vermeil De Conchard, Guy; Simonin, Gilles; Bertheux, Helene; Weaver, Richard J; Johnson, Robert L; Liguori, Michael J; Clausznitzer, Diana; Stevens, James L; Goldring, Christopher E; Copple, Ian M

Detection of Hepatic Drug Metabolite-Specific T-Cell Responses Using a Human Hepatocyte, Immune Cell Coculture System

利用人肝细胞-免疫细胞共培养系统检测肝脏药物代谢物特异性T细胞反应

Ali, Serat-E; Meng, Xiaoli; Kafu, Laila; Hammond, Sean; Zhao, Qing; Ogese, Monday; Sison-Young, Rowena; Jones, Robert; Chan, Benjamin; Livoti, Lucia; Sun, Yonghu; Sun, Lele; Liu, Hong; Topping, Anthony; Goldring, Christopher; Zhang, Furen; Naisbitt, Dean John

Study design for development of novel safety biomarkers of drug-induced liver injury by the translational safety biomarker pipeline (TransBioLine) consortium: a study protocol for a nested case-control study

转化安全生物标志物研发管线(TransBioLine)联盟开发新型药物性肝损伤安全生物标志物的研究设计:一项嵌套病例对照研究的研究方案

Grove, Jane I; Stephens, Camilla; Lucena, M Isabel; Andrade, Raúl J; Weber, Sabine; Gerbes, Alexander; Bjornsson, Einar S; Stirnimann, Guido; Daly, Ann K; Hackl, Matthias; Khamina-Kotisch, Kseniya; Marin, Jose J G; Monte, Maria J; Paciga, Sara A; Lingaya, Melanie; Forootan, Shiva S; Goldring, Christopher E P; Poetz, Oliver; Lombaard, Rudolf; Stege, Alexandra; Bjorrnsson, Helgi K; Robles-Diaz, Mercedes; Li, Dingzhou; Tran, Thi Dong Binh; Ramaiah, Shashi K; Samodelov, Sophia L; Kullak-Ublick, Gerd A; Aithal, Guruprasad P

Interruption of bile acid uptake by hepatocytes after acetaminophen overdose ameliorates hepatotoxicity

对乙酰氨基酚过量后,阻断肝细胞对胆汁酸的吸收可减轻肝毒性。

Ghallab, Ahmed; Hassan, Reham; Hofmann, Ute; Friebel, Adrian; Hobloss, Zaynab; Brackhagen, Lisa; Begher-Tibbe, Brigitte; Myllys, Maiju; Reinders, Joerg; Overbeck, Nina; Sezgin, Selahaddin; Zühlke, Sebastian; Seddek, Abdel-Latif; Murad, Walaa; Brecklinghaus, Tim; Kappenberg, Franziska; Rahnenführer, Jörg; González, Daniela; Goldring, Christopher; Copple, Ian M; Marchan, Rosemarie; Longerich, Thomas; Vucur, Mihael; Luedde, Tom; Urban, Stephan; Canbay, Ali; Schreiter, Thomas; Trauner, Michael; Akakpo, Jephte Y; Olyaee, Mojtaba; Curry, Steven C; Sowa, Jan-Peter; Jaeschke, Hartmut; Hoehme, Stefan; Hengstler, Jan G

Safety perspectives on presently considered drugs for the treatment of COVID-19

目前考虑用于治疗 COVID-19 的药物的安全性展望

Penman, Sophie L; Kiy, Robyn T; Jensen, Rebecca L; Beoku-Betts, Christopher; Alfirevic, Ana; Back, David; Khoo, Saye H; Owen, Andrew; Pirmohamed, Munir; Park, B Kevin; Meng, Xiaoli; Goldring, Christopher E; Chadwick, Amy E