日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Joint damage is more severe following a single bout than multiple bouts of high magnitude loading in mice

小鼠单次高强度负荷造成的关节损伤比多次高强度负荷造成的关节损伤更为严重。

Ziemian, Sophia N; Antoinette, Adrien Y; Witkowski, Ana; Otero, Miguel; Goldring, Steven R; Goldring, Mary B; van der Meulen, Marjolein C H

PTH treatment before cyclic joint loading improves cartilage health and attenuates load-induced osteoarthritis development in mice

周期性关节负荷前进行 PTH 治疗可改善小鼠软骨健康并减轻负荷诱发的骨关节炎发展

Adrien Y Antoinette, Sophia N Ziemian, Allison R Brown, Erin B Hudson, Carolyn Chlebek, Timothy M Wright, Steven R Goldring, Mary B Goldring, Miguel Otero, Marjolein C H van der Meulen

Single dose thermoresponsive dexamethasone prodrug completely mitigates joint pain for 15 weeks in a murine model of osteoarthritis

单剂量热敏性地塞米松前药可在小鼠骨关节炎模型中完全缓解关节疼痛,疗效持续15周。

Chen, Ningrong; Wei, Xin; Zhao, Gang; Jia, Zhenshan; Fu, Xin; Jiang, Haochen; Xu, Xiaoke; Zhao, Zhifeng; Singh, Purva; Lessard, Samantha; Otero, Miguel; Goldring, Mary B; Goldring, Steven R; Wang, Dong

Identification of formulation parameters that affect the analgesic efficacy of ProGel-Dex - A thermoresponsive polymeric dexamethasone prodrug for chronic arthritis pain relief

确定影响ProGel-Dex镇痛效果的制剂参数——ProGel-Dex是一种用于缓解慢性关节炎疼痛的热响应性聚合物地塞米松前药

Wei, Xin; Zhao, Gang; Chen, Ningrong; Xu, Xiaoke; Jiang, Haochen; Tran, Daniel; Glissmeyer, Evan; Goldring, Mary B; Goldring, Steven R; Wang, Dong

Thermoresponsive Polymeric Hydromorphone Prodrug Provides Sustained Local Analgesia without Apparent Adverse Effects

热响应性聚合物氢吗啡酮前药可提供持续的局部镇痛作用,且无明显不良反应。

Jia, Zhenshan; Wei, Xin; Chen, Ningrong; Xu, Xiaoke; Zhao, Gang; Fu, Xin; Wang, Hanjun; Goldring, Mary B; Goldring, Steven R; Wang, Dong

Contribution of joint tissue properties to load-induced osteoarthritis

关节组织特性对负荷诱发性骨关节炎的影响

Ayobami, Olufunmilayo O; Goldring, Steven R; Goldring, Mary B; Wright, Timothy M; van der Meulen, Marjolein C H

Do Synovial Inflammation and Meniscal Degeneration Impact Clinical Outcomes of Patients Undergoing Arthroscopic Partial Meniscectomy? A Histological Study

滑膜炎症和半月板退化是否会影响接受关节镜部分半月板切除术的患者的临床结果?一项组织学研究

Eleonora Olivotto, Elisa Belluzzi, Assunta Pozzuoli, Augusto Cigolotti, Manuela Scioni, Steven R Goldring, Mary B Goldring, Pietro Ruggieri, Roberta Ramonda, Brunella Grigolo, Giovanni Trisolino, Marta Favero

Macroscopic Synovial Inflammation Correlates with Symptoms and Cartilage Lesions in Patients Undergoing Arthroscopic Partial Meniscectomy: A Clinical Study

关节镜下部分半月板切除术患者的宏观滑膜炎症与症状和软骨损伤相关:一项临床研究

Olivotto, Eleonora; Trisolino, Giovanni; Belluzzi, Elisa; Lazzaro, Antonello; Strazzari, Alessandro; Pozzuoli, Assunta; Cigolotti, Augusto; Ruggieri, Pietro; Evangelista, Andrea; Ometto, Francesca; Stallone, Stefano; Goldring, Steven R; Goldring, Mary B; Ramonda, Roberta; Grigolo, Brunella; Favero, Marta

Transcriptomic and epigenomic analyses uncovered Lrrc15 as a contributing factor to cartilage damage in osteoarthritis

转录组学和表观基因组学分析揭示了Lrrc15是骨关节炎软骨损伤的一个促成因素

Singh, Purva; Wang, Mengying; Mukherjee, Piali; Lessard, Samantha G; Pannellini, Tania; Carballo, Camila B; Rodeo, Scott A; Goldring, Mary B; Otero, Miguel

LOXL2 promotes aggrecan and gender-specific anabolic differences to TMJ cartilage

LOXL2促进聚集蛋白聚糖的形成,并导致颞下颌关节软骨的性别特异性合成代谢差异

Tashkandi, Mustafa M; Alsaqer, Saqer F; Alhousami, Thabet; Ali, Faiza; Wu, Yu-Chiao; Shin, Jennifer; Mehra, Pushkar; Wolford, Larry M; Gerstenfeld, Louis C; Goldring, Mary B; Bais, Manish V