Pathway- and expression level-dependent effects of oncogenic N-Ras: p27(Kip1) mislocalization by the Ral-GEF pathway and Erk-mediated interference with Smad signaling.

致癌 N-Ras 的通路和表达水平依赖性效应：Ral-GEF 通路导致 p27(Kip1) 错误定位，以及 Erk 介导的对 Smad 信号的干扰