β-Hydroxybutyrate upregulates hepatic histone β-hydroxybutyrylation modification, promotes the expression of PPARα, and alleviates the hepatic steatosis in MASLD
β-羟基丁酸可上调肝脏组蛋白β-羟基丁酰化修饰,促进PPARα表达,并减轻MASLD中的肝脂肪变性。
期刊:Clinical Epigenetics
影响因子:4.4
doi:10.1186/s13148-026-02111-2
Li, Dongze; Zhang, Li; Li, Yanqun; Wu, Jidi; Mou, Yulin; He, Yanqiu; Zhou, Tingting; Gong, Qiming; Ma, Linqiang; Xu, Yong; Huang, Wei; Gao, Chenlin