NF-kappaB is a negative regulator of IL-1beta secretion as revealed by genetic and pharmacological inhibition of IKKbeta.
通过对 IKKβ 进行基因和药理学抑制，发现 NF-κB 是 IL-1β 分泌的负调控因子
期刊:Cell
影响因子:42.5
doi:10.1016/j.cell.2007.07.009
Greten Florian R, Arkan Melek C, Bollrath Julia, Hsu Li-Chung, Goode Jason, Miething Cornelius, Göktuna Serkan I, Neuenhahn Michael, Fierer Joshua, Paxian Stephan, Van Rooijen Nico, Xu Yajun, O'Cain Timothy, Jaffee Bruce B, Busch Dirk H, Duyster Justus, Schmid Roland M, Eckmann Lars, Karin Michael
