日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

The long non-coding RNA CRNDE stabilises SIRT1 protein and influences Hedgehog signalling in multiple myeloma

长链非编码RNA CRNDE可稳定SIRT1蛋白并影响多发性骨髓瘤中的Hedgehog信号通路。

Zocchi, Simone; Trichet, Pauline; Guernalec, Paloma; Agdada, Manal; Alonso Bartolomé, Ana; Ogor, Vincent; Choisy, Caroline; Vias, Carine; Sabaté-Cadenas, Xavier; Bories, Jean-Christophe; Goodhardt, Michele; Shkumatava, Alena; Garrick, David

Altered X-chromosome inactivation predisposes to autoimmunity

X染色体失活异常易导致自身免疫性疾病

Christophe Huret ,Léa Ferrayé ,Antoine David ,Myriame Mohamed ,Nicolas Valentin ,Frédéric Charlotte ,Magali Savignac ,Michele Goodhardt ,Jean-Charles Guéry ,Claire Rougeulle ,Céline Morey

MAIT cell inhibition promotes liver fibrosis regression via macrophage phenotype reprogramming

MAIT细胞抑制通过巨噬细胞表型重编程促进肝纤维化消退

Morgane Mabire ,Pushpa Hegde ,Adel Hammoutene # ,Jinghong Wan # ,Charles Caër # ,Rola Al Sayegh ,Mathilde Cadoux ,Manon Allaire ,Emmanuel Weiss ,Tristan Thibault-Sogorb ,Olivier Lantz ,Michèle Goodhardt ,Valérie Paradis ,Pierre de la Grange ,Hélène Gilgenkrantz ,Sophie Lotersztajn

Multimodal cartography of human lymphopoiesis reveals B and T/NK/ILC lineages are subjected to differential regulation

人类淋巴细胞生成的多模态图谱显示,B细胞和T/NK/ILC谱系受到不同的调控。

Kutaiba Alhaj Hussen ,Emna Chabaane ,Elisabeth Nelson ,Shalva Lekiashvili ,Samuel Diop ,Seydou Keita ,Bertrand Evrard ,Aurélie Lardenois ,Marc Delord ,Els Verhoeyen ,Kerstin Cornils ,Zeinab Kasraian ,Elizabeth A Macintyre ,Ana Cumano ,David Garrick ,Michele Goodhardt ,Guillaume P Andrieu ,Vahid Asnafi ,Frederic Chalmel ,Bruno Canque

CAR-T cells derived from multiple myeloma patients at diagnosis have improved cytotoxic functions compared to those produced at relapse or following daratumumab treatment

与复发时或接受达雷妥尤单抗治疗后产生的CAR-T细胞相比,从多发性骨髓瘤患者确诊时获得的CAR-T细胞具有更强的细胞毒性功能。

Abecassis, Audrey; Roders, Nathalie; Fayon, Maxime; Choisy, Caroline; Nelson, Elisabeth; Harel, Stephanie; Royer, Bruno; Villesuzanne, Camille; Talbot, Alexis; Garrick, David; Goodhardt, Michele; Fermand, Jean-Paul; Burbridge, Mike; Arnulf, Bertrand; Bories, Jean-Christophe

The long non-coding RNA CRNDE regulates growth of multiple myeloma cells via an effect on IL6 signalling

长链非编码 RNA CRNDE 通过影响 IL6 信号传导来调节多发性骨髓瘤细胞的生长

Antoine David, Simone Zocchi, Alexis Talbot, Caroline Choisy, Ashley Ohnona, Julien Lion, Wendy Cuccuini, Jean Soulier, Bertrand Arnulf, Jean-Christophe Bories, Michele Goodhardt, David Garrick

Reduced RNA turnover as a driver of cellular senescence

RNA 周转率降低是细胞衰老的驱动因素

Nowsheen Mullani, Yevheniia Porozhan, Adèle Mangelinck, Christophe Rachez, Mickael Costallat, Eric Batsché, Michele Goodhardt, Giovanni Cenci, Carl Mann, Christian Muchardt

Human Platelet Lysate versus Fetal Calf Serum: These Supplements Do Not Select for Different Mesenchymal Stromal Cells

人血小板裂解物与胎牛血清:这些补充剂不会选择不同的间充质基质细胞

Eduardo Fernandez-Rebollo, Birgit Mentrup, Regina Ebert, Julia Franzen, Giulio Abagnale, Torsten Sieben, Alina Ostrowska, Per Hoffmann, Pierre-François Roux, Björn Rath, Michele Goodhardt, Jean-Marc Lemaitre, Oliver Bischof, Franz Jakob, Wolfgang Wagner3

Age-Associated Decrease of the Histone Methyltransferase SUV39H1 in HSC Perturbs Heterochromatin and B Lymphoid Differentiation

造血干细胞中组蛋白甲基转移酶SUV39H1的年龄相关性下降会扰乱异染色质和B淋巴细胞分化

Djeghloul, Dounia; Kuranda, Klaudia; Kuzniak, Isabelle; Barbieri, Daniela; Naguibneva, Irina; Choisy, Caroline; Bories, Jean-Christophe; Dosquet, Christine; Pla, Marika; Vanneaux, Valérie; Socié, Gérard; Porteu, Françoise; Garrick, David; Goodhardt, Michele

AF1q/MLLT11 regulates the emergence of human prothymocytes through cooperative interaction with the Notch signaling pathway

AF1q/MLLT11 通过与 Notch 信号通路协同作用来调节人类胸腺原细胞的出现

Aude Parcelier, Nesrine Maharzi, Marc Delord, Macarena Robledo-Sarmiento, Elisabeth Nelson, Halima Belakhdar-Mekid, Marika Pla, Klaudia Kuranda, Veronique Parietti, Michele Goodhardt, Nicolas Legrand, Irwin D Bernstein, Jean Claude Gluckman, François Sigaux, Bruno Canque