日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Taperin bundles F-actin at stereocilia pivot points enabling optimal lifelong mechanosensitivity.

Taperin 将 F-肌动蛋白束固定在立体纤毛的枢轴点,从而实现最佳的终生机械敏感性

Belyantseva Inna A, Liu Chang, Dragich Abigail K, Miyoshi Takushi, Inagaki Sayaka, Imtiaz Ayesha, Tona Risa, Zuluaga-Osorio Karen Sofia, Hadi Shadan, Wilson Elizabeth, Morozko Eva, Olszewski Rafal, Yousaf Rizwan, Sokolova Yuliya, Riordan Gavin P, Aston S Andrew, Rehman Atteeq U, Fenollar Ferrer Cristina, Wisniewski Jan, Gu Shoujun, Nayak Gowri, Goodyear Richard J, Li Jinan, Krey Jocelyn F, Wafa Talah, Faridi Rabia, Adadey Samuel Mawuli, Drummond Meghan, Perrin Benjamin, Winkler Dennis C, Starost Matthew F, Cheng Hui, Fitzgerald Tracy, Richardson Guy P, Dong Lijin, Barr-Gillespie Peter G, Hoa Michael, Frolenkov Gregory I, Friedman Thomas B, Zhao Bo

Identification of ion-channel modulators that protect against aminoglycoside-induced hair cell death

鉴定能够保护毛细胞免受氨基糖苷类药物诱导死亡的离子通道调节剂

Kenyon, Emma J; Kirkwood, Nerissa K; Kitcher, Siân R; O'Reilly, Molly; Derudas, Marco; Cantillon, Daire M; Goodyear, Richard J; Secker, Abigail; Baxendale, Sarah; Bull, James C; Waddell, Simon J; Whitfield, Tanya T; Ward, Simon E; Kros, Corné J; Richardson, Guy P

The acquisition of mechano-electrical transducer current adaptation in auditory hair cells requires myosin VI

听觉毛细胞获得机械电换能器电流适应需要肌球蛋白VI

Marcotti, Walter; Corns, Laura F; Goodyear, Richard J; Rzadzinska, Agnieszka K; Avraham, Karen B; Steel, Karen P; Richardson, Guy P; Kros, Corné J

Carcinoembryonic antigen-related cell adhesion molecule 16 interacts with alpha-tectorin and is mutated in autosomal dominant hearing loss (DFNA4)

癌胚抗原相关细胞粘附分子 16 与 α-tectorin 相互作用,并在常染色体显性遗传性听力损失 (DFNA4) 中发生突变。

Zheng, Jing; Miller, Katharine K; Yang, Tao; Hildebrand, Michael S; Shearer, A Eliot; DeLuca, Adam P; Scheetz, Todd E; Drummond, Jennifer; Scherer, Steve E; Legan, P Kevin; Goodyear, Richard J; Richardson, Guy P; Cheatham, Mary Ann; Smith, Richard J; Dallos, Peter

Stereocilin connects outer hair cell stereocilia to one another and to the tectorial membrane.

立体纤毛蛋白将外毛细胞的立体纤毛彼此连接,并与盖膜连接

Verpy Elisabeth, Leibovici Michel, Michalski Nicolas, Goodyear Richard J, Houdon Carine, Weil Dominique, Richardson Guy P, Petit Christine

In vivo and in vitro effects of two novel gamma-actin (ACTG1) mutations that cause DFNA20/26 hearing impairment

两种导致 DFNA20/26 听力障碍的新型 γ-肌动蛋白 (ACTG1) 突变的体内和体外效应

Morín, Matías; Bryan, Keith E; Mayo-Merino, Fernando; Goodyear, Richard; Mencía, Angeles; Modamio-Høybjør, Silvia; del Castillo, Ignacio; Cabalka, Jessica M; Richardson, Guy; Moreno, Felipe; Rubenstein, Peter A; Moreno-Pelayo, Miguel Angel

A mutation in CCDC50, a gene encoding an effector of epidermal growth factor-mediated cell signaling, causes progressive hearing loss.

CCDC50 基因(编码表皮生长因子介导的细胞信号传导效应因子)发生突变会导致进行性听力丧失

Modamio-Hoybjor Silvia, Mencia Angeles, Goodyear Richard, del Castillo Ignacio, Richardson Guy, Moreno Felipe, Moreno-Pelayo Miguel Angel

Stereociliary myosin-1c receptors are sensitive to calcium chelation and absent from cadherin 23 mutant mice

立体纤毛肌球蛋白-1c受体对钙螯合敏感,且在钙黏蛋白23突变小鼠中缺失。

Phillips, Kelli R; Tong, Song; Goodyear, Richard; Richardson, Guy P; Cyr, Janet L

The tip-link antigen, a protein associated with the transduction complex of sensory hair cells, is protocadherin-15

顶端连接抗原是一种与感觉毛细胞转导复合物相关的蛋白质,即原钙黏蛋白-15。

Ahmed, Zubair M; Goodyear, Richard; Riazuddin, Saima; Lagziel, Ayala; Legan, P Kevin; Behra, Martine; Burgess, Shawn M; Lilley, Kathryn S; Wilcox, Edward R; Riazuddin, Sheikh; Griffith, Andrew J; Frolenkov, Gregory I; Belyantseva, Inna A; Richardson, Guy P; Friedman, Thomas B

The structure of tip links and kinocilial links in avian sensory hair bundles

鸟类感觉毛束中顶端连接和动纤毛连接的结构

Tsuprun, Vladimir; Goodyear, Richard J; Richardson, Guy P