Autophosphorylation of oncoprotein TEL-ABL in myeloid and lymphoid cells confers resistance to the allosteric ABL inhibitor asciminib.
髓系和淋巴系细胞中癌蛋白 TEL-ABL 的自身磷酸化赋予了对变构 ABL 抑制剂 asciminib 的耐药性
期刊:Science Signaling
影响因子:6.6
doi:10.1126/scisignal.adt5931
Muratcioglu Serena, Eide Christopher A, Hung Chien-Lun, Gorday Kent, Sumpena Emily, Zuo Wenqi, Groves Jay T, Druker Brian J, Kuriyan John
