日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Benzoxazole-derivatives enhance progranulin expression and reverse the aberrant lysosomal proteome caused by GRN haploinsufficiency

苯并恶唑衍生物可增强前颗粒蛋白的表达,并逆转由 GRN 单倍体不足引起的溶酶体蛋白质组异常

Rachel Tesla #, Charlotte Guhl #, Gordon C Werthmann #, Danielle Dixon, Basar Cenik, Yesu Addepalli, Jue Liang, Daniel M Fass, Zachary Rosenthal, Stephen J Haggarty, Noelle S Williams, Bruce A Posner, Joseph M Ready, Joachim Herz

Epigenetic modulation through BET bromodomain inhibitors as a novel therapeutic strategy for progranulin-deficient frontotemporal dementia

通过 BET 溴结构域抑制剂进行表观遗传调控作为治疗前颗粒蛋白缺乏型额颞叶痴呆的新策略

Zachary C Rosenthal, Daniel M Fass, N Connor Payne, Angela She, Debasis Patnaik, Krista M Hennig, Rachel Tesla, Gordon C Werthmann, Charlotte Guhl, Surya A Reis, Xiaoyu Wang, Yueting Chen, Michael Placzek, Noelle S Williams, Jacob Hooker, Joachim Herz, Ralph Mazitschek, Stephen J Haggarty

Regulation of the hippocampal translatome by Apoer2-ICD release

Apoer2-ICD 释放对海马翻译组的调节

Catherine R Wasser #, Gordon C Werthmann #, Eric M Hall, Kristina Kuhbandner, Connie H Wong, Murat S Durakoglugil, Joachim Herz

Apoer2-ICD-dependent regulation of hippocampal ribosome mRNA loading

Apoer2-ICD依赖性调节海马核糖体mRNA的加载

Catherine Wasser, Gordon C Werthmann, Eric M Hall, Kristina Kuhbandner, Connie H Wong, Murat S Durakoglugil, Joachim Herz