日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

A phase 1 study of berzosertib (M6620, VX-970) in combination with cisplatin and radiation in patients with locally advanced head and neck squamous cell carcinoma (ETCTN 9950)

一项针对局部晚期头颈部鳞状细胞癌患者的 1 期研究,评估 berzosertib (M6620, VX-970) 与顺铂和放射治疗的疗效 (ETCTN 9950)

Bhatia, Aarti; Chen, Zhengjia; Zhang, Yuji; Bruce, Justine Yang; Arnold, Susanne; Kaur, Varinder; Riess, Jonathan W; Fenton, Moon; Burtness, Barbara; Saba, Nabil F; Tara, Harold; Steuer, Conor E; Shin, Dong M; Wasp, Garrett; Davis, Thomas H; Patel, Malini; Schmitz, John C; Bhateja, Priyanka; Diavolitsis, Virginia; Zandberg, Dan P; Mitchell, Darrion L; Kiesel, Brian F; Kunos, Charles; Gore, Steven D; Carducci, Michael; Beumer, Jan H; Owonikoko, Taofeek K

Elderberry wine and promyelocytic leukemia

接骨木果酒与早幼粒细胞白血病

Gore, Steven D

Phase 1 clinical trial of the ataxia telangiectasia and Rad3-related inhibitor berzosertib with irinotecan in patients with advanced solid tumors (ETCTN 9938)

共济失调毛细血管扩张症和 Rad3 相关抑制剂 berzosertib 与伊立替康联合治疗晚期实体瘤患者的 1 期临床试验 (ETCTN 9938)

Villaruz, Liza C; Jin, Jingxiao; Wang, Hong; Lee, James J; Luke, Jason J; Rhee, John C; Waqar, Saiama N; Shapiro, Geoffrey I; Cleary, James; Davar, Diwakar; Burns, Timothy F; Verma, Rashmi; Amin, Manik; Appleman, Leonard; Ciombor, Kristen K; Davis, Elizabeth J; Riess, Jonathan W; Dees, E Claire; Kim, Edward J; Cardin, Dana; Guo, Jianxia; Christner, Susan M; Deppas, Joshua; Parise, Angelina M; Schmitz, John C; Guerrouahen, Bella S; Suchko, Michael; Contreras, Alejandro; Li, Li; Ferry-Galow, Katherine V; Chang, Ting-Chia; Jiwani, Shahanawaz; Bakkenist, Christopher J; Chu, Edward; Gore, Steven D; Beumer, Jan H

The ATR Inhibitor Elimusertib in Combination with Cisplatin in Patients with Advanced Solid Tumors: A California Cancer Consortium Phase I Trial (NCI 10404)

ATR抑制剂Elimusertib联合顺铂治疗晚期实体瘤患者:加州癌症联盟I期试验(NCI 10404)

Parikh, Mamta; Uboha, Nataliya V; Takebe, Naoko; Tam, Kit; Bedard, Philippe L; Wisinski, Kari B; Mittra, Arjun; Yin, Ming; Yang, Yuanquan; Noonan, Anne M; Holleran, Julianne L; Ruel, Christopher; Frankel, Paul; Beumer, Jan H; Newman, Edward M; Danilov, Alexey V; Gore, Steven D; Lara, Primo N Jr

High-throughput combination screening of Pidnarulex and other G-quadruplex ligands in multi-cell type tumor spheroids

在多细胞类型肿瘤球体中对 Pidnarulex 和其他 G-四链体配体进行高通量组合筛选

Dexheimer, Thomas S; Coussens, Nathan P; Silvers, Thomas; Juneja, Poorva; Jones, Eric; Gore, Steven D; Kunkel, Mark W; Doroshow, James H; Teicher, Beverly A

RNA processing kinase inhibitors and epigenetic inhibitors in combination with oncology drugs or investigational agents in multi-cell type patient-derived tumor cell line spheroids

RNA加工激酶抑制剂和表观遗传抑制剂与肿瘤药物或研究性药物联合用于多细胞类型患者来源的肿瘤细胞系球体

Teicher, Beverly A; Dexheimer, Thomas S; Silvers, Thomas; Coussens, Nathan P; Jones, Eric; Gore, Steven D; Kunkel, Mark; Doroshow, James H

A phase 1 study of the combination of BH3-mimetic, navitoclax, and mTORC1/2 inhibitor, vistusertib, in patients with advanced solid tumors

一项针对晚期实体瘤患者的 I 期研究,评估 BH3 模拟物 navitoclax 和 mTORC1/2 抑制剂 vistusertib 联合用药的疗效。

Scott, Susan C; Farago, Anna; Lai, W Victoria; Zahurak, Marianna; Rudek, Michelle A; Murray, Judy; Carducci, Michael A; Uziel, Tamar; Takebe, Naoko; Gore, Steven D; Rudin, Charles M; Hann, Christine L

Quantitation of Tuvusertib (M1774) in Human Plasma by LC-MS/MS

采用液相色谱-串联质谱法定量人血浆中的妥维替尼(M1774)

Le, Tien V; Parise, Robert A; Holleran, Julianne L; Bakkenist, Christopher J; Synold, Timothy; Feng, Ye; Cote, Gregory M; Gore, Steven D; Beumer, Jan H

RNA processing kinase inhibitors and epigenetic inhibitors in combination with oncology drugs or investigational agents in multi-cell type patient-derived tumor cell line spheroids.

RNA 加工激酶抑制剂和表观遗传抑制剂与肿瘤药物或研究性药物联合用于多细胞类型患者来源的肿瘤细胞系球体

Teicher Beverly A, Dexheimer Thomas S, Silvers Thomas, Coussens Nathan P, Jones Eric, Gore Steven D, Kunkel Mark, Doroshow James H

Blinatumomab for MRD-Negative Acute Lymphoblastic Leukemia in Adults

Blinatumomab 用于治疗成人 MRD 阴性急性淋巴细胞白血病

Litzow, Mark R; Sun, Zhuoxin; Mattison, Ryan J; Paietta, Elisabeth M; Roberts, Kathryn G; Zhang, Yanming; Racevskis, Janis; Lazarus, Hillard M; Rowe, Jacob M; Arber, Daniel A; Wieduwilt, Matthew J; Liedtke, Michaela; Bergeron, Julie; Wood, Brent L; Zhao, Yaqi; Wu, Gang; Chang, Ti-Cheng; Zhang, Wenchao; Pratz, Keith W; Dinner, Shira N; Frey, Noelle; Gore, Steven D; Bhatnagar, Bhavana; Atallah, Ehab L; Uy, Geoffrey L; Jeyakumar, Deepa; Lin, Tara L; Willman, Cheryl L; DeAngelo, Daniel J; Patel, Shejal B; Elliott, Michelle A; Advani, Anjali S; Tzachanis, Dimitrios; Vachhani, Pankit; Bhave, Rupali R; Sharon, Elad; Little, Richard F; Erba, Harry P; Stone, Richard M; Luger, Selina M; Mullighan, Charles G; Tallman, Martin S