日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Rheb membrane orientation dynamics and functional consequences elucidated by molecular simulations, single-molecule-FRET and signaling assays

通过分子模拟、单分子FRET和信号传导分析阐明Rheb膜取向动力学及其功能后果

Hutchins, Chase M; Pagba, Cynthia; Verma, Geetika; Jakubec, Jacob; Du, Guangwei; Jayaraman, Vasanthi; Gorfe, Alemayehu A

BMAL1-HIF2A heterodimer modulates circadian variations of myocardial injury

BMAL1-HIF2A异二聚体调节心肌损伤的昼夜节律变化

Wei Ruan # ,Tao Li # ,In Hyuk Bang # ,Jaewoong Lee # ,Wankun Deng ,Xinxin Ma ,Cong Luo ,Fang Du ,Seung-Hee Yoo ,Boyun Kim ,Jiwen Li ,Xiaoyi Yuan ,Katherine Figarella ,Yu A An ,Yin-Ying Wang ,Yafen Liang ,Matthew DeBerge ,Dongze Zhang ,Zhen Zhou ,Yanyu Wang ,Joshua M Gorham ,Jonathan G Seidman ,Christine E Seidman ,Sary F Aranki ,Ragini Nair ,Lei Li ,Jagat Narula ,Zhongming Zhao ,Alemayehu A Gorfe ,Jochen D Muehlschlegel ,Kuang-Lei Tsai ,Holger K Eltzschig

RAS-membrane interaction and oligomerization: there is more than meets the eye

RAS-膜相互作用和寡聚化:远不止表面看起来那么简单

Sianoya, Abraham C; Bhardwaj, Vijay K; Gorfe, Alemayehu A

Differential Lipid Binding Specificities of RAP1A and RAP1B are Encoded by the Amino Acid Sequence of the Membrane Anchors

RAP1A 和 RAP1B 的差异性脂质结合特异性是由膜锚定氨基酸序列编码的。

Mussie K Araya ,Wei Chen ,Yuepeng Ke ,Yubin Zhou ,Alemayehu A Gorfe ,John F Hancock ,Junchen Liu

From disorder comes function: Regulation of small GTPase function by intrinsically disordered lipidated membrane anchor

无序中蕴含功能:固有无序的脂化膜锚对小GTP酶功能的调控

Hutchins, Chase M; Gorfe, Alemayehu A

Intrinsically Disordered Membrane Anchors of Rheb, RhoA, and DiRas3 Small GTPases: Molecular Dynamics, Membrane Organization, and Interactions

Rheb、RhoA 和 DiRas3 小 GTP 酶的固有无序膜锚定:分子动力学、膜组织和相互作用

Hutchins, Chase M; Gorfe, Alemayehu A

Intrinsically disordered membrane anchors of Rheb, RhoA and DiRas3 small GTPases: Molecular dynamics, membrane organization, and interactions

Rheb、RhoA 和 DiRas3 小 GTP 酶的固有无序膜锚定:分子动力学、膜组织和相互作用

Hutchins, Chase M; Gorfe, Alemayehu A

Conformational ensemble-dependent lipid recognition and segregation by prenylated intrinsically disordered regions in small GTPases

小GTP酶中异戊二烯化固有无序区对构象集合依赖性脂质的识别和分离

Araya, Mussie K; Gorfe, Alemayehu A

Membrane anchoring of the DIRAS3 N-terminal extension permits tumor suppressor function

DIRAS3 N 端延伸的膜锚定可实现肿瘤抑制功能

Xiaowen Liang, Sung Yun Jung, Lon Wolf Fong, Gamze Bildik, Joshua P Gray, Weiqun Mao, Shuxing Zhang, Steven W Millward, Alemayehu A Gorfe, Yong Zhou, Zhen Lu, Robert C Bast Jr

Small-Molecule Inhibition of KRAS through Conformational Selection

通过构象选择抑制KRAS的小分子

Pagba, Cynthia V; Gupta, Amit K; Gorfe, Alemayehu A