日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Development of a targeted BioPROTAC degrader selective for misfolded SOD1

开发一种针对错误折叠的SOD1的靶向BioPROTAC降解剂

Chisholm, Christen G; Bartlett, Rachael; Brown, Mikayla L; Proctor, Emma-Jayne; Farrawell, Natalie E; Gorman, Jody; Delerue, Fabien; Ittner, Lars M; Vine-Perrow, Kara L; Ecroyd, Heath; Cashman, Neil R; Saunders, Darren N; McAlary, Luke; Lum, Jeremy S; Yerbury, Justin J

A polytherapy approach demonstrates therapeutic efficacy for the treatment of SOD1 associated amyotrophic lateral sclerosis.

多药联合疗法对治疗 SOD1 相关肌萎缩侧索硬化症具有疗效

Lum Jeremy S, Brown Mikayla L, Farrawell Natalie E, Bartlett Rachael, Chisholm Christen G, Gorman Jody, Dosseto Anthony, Dux Florian, McInnes Lachlan E, Ecroyd Heath, McAlary Luke, Crouch Peter J, Donnelly Paul S, Yerbury Justin J

Fibrinogen-binding M-related proteins facilitate the recruitment of plasminogen by Streptococcus pyogenes.

纤维蛋白原结合 M 相关蛋白促进化脓性链球菌募集纤溶酶原

Proctor Emma-Jayne, Frost Hannah R, Mantri Bhanu, Satapathy Sandeep, Botquin Gwenaëlle, Gorman Jody, De Oliveira David M P, McArthur Jason, Davies Mark R, Tolun Gökhan, Botteaux Anne, Smeesters Pierre, Sanderson-Smith Martina

Current Understanding of Group A Streptococcal Biofilms

目前对A组链球菌生物膜的认识

Vyas, Heema K N; Proctor, Emma-Jayne; McArthur, Jason; Gorman, Jody; Sanderson-Smith, Martina