Enhancement of docetaxel-induced cytotoxicity and apoptosis by all-trans retinoic acid (ATRA) through downregulation of survivin (BIRC5), MCL-1 and LTbeta-R in hormone- and drug resistant prostate cancer cell line, DU-145
全反式维甲酸 (ATRA) 通过下调激素和药物耐药性前列腺癌细胞系 DU-145 中的 survivin (BIRC5)、MCL-1 和 LTbeta-R 来增强多西他赛诱导的细胞毒性和细胞凋亡
期刊:Journal of Experimental & Clinical Cancer Research
影响因子:12.8
doi:10.1186/1756-9966-27-37
Kucukzeybek, Yuksel; Gul, Mustafa K; Cengiz, Ercument; Erten, Cigdem; Karaca, Burcak; Gorumlu, Gurbuz; Atmaca, Harika; Uzunoglu, Selim; Karabulut, Bulent; Sanli, Ulus A; Uslu, Ruchan
肿瘤
凋亡
表观遗传
肿瘤免疫
毒理研究
ATR
细胞生物学
前列腺癌
免疫/内分泌