日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Bacteriophages mobilize bacterial defense systems via lateral transduction

噬菌体通过横向转导激活细菌防御系统。

Kuang, Xu; Gorzynski, Jamie; Touchon, Marie; Shkoporov, Andrey; Rocha, Eduardo P C; Fitzgerald, J Ross; Chen, John; Rostøl, Jakob T; Penadés, José R

Bacterial metabolic remodeling by convergent evolution unlocks nutrient availability after a host switch

趋同进化导致的细菌代谢重塑,使得宿主转换后营养物质的可用性得以恢复。

Pickering, Amy C; Gorzynski, Jamie; Taylor-Joyce, Grace; Evans, Rhodri; Fox, Willow; Melo, Pedro; Alves, Joana; Schlauch, Hannah; Sargison, Fiona; Yebra, Gonzalo; Ring, Natalie; Fitzgerald, J Ross

Integration of transcriptomics and long-read genomics prioritizes structural variants in rare disease

转录组学和长读长基因组学的整合优先考虑罕见病中的结构变异

Jensen, Tanner D; Ni, Bohan; Reuter, Chloe M; Gorzynski, John E; Fazal, Sarah; Bonner, Devon; Ungar, Rachel A; Goddard, Pagé C; Raja, Archana; Ashley, Euan A; Bernstein, Jonathan A; Zuchner, Stephan; Greicius, Michael D; Montgomery, Stephen B; Schatz, Michael C; Wheeler, Matthew T; Battle, Alexis

Discovery of Biofilm-Inhibiting Compounds to Enhance Antibiotic Effectiveness Against M. abscessus Infections

发现生物膜抑制剂可增强抗生素对脓肿分枝杆菌感染的疗效

Dzalamidze, Elizaveta; Gorzynski, Mylene; Vande Voorde, Rebecca; Nelson, Dylan; Danelishvili, Lia

Ensilication preserves high-molecular weight native DNA for clinical long-read sequencing

硅化技术能够保留高分子量天然DNA,用于临床长读长测序。

Ferrasse, Alexis; Mendez, Rodrigo; Gorzynski, John E; Reuter, Chloe; Carter, Jennefer N; Bernstein, Jonathan A; Wheeler, Matthew T; Banal, James L; Ashley, Euan A

Long-read genome sequencing and multi-omics in aging and neurodegeneration

长读长基因组测序和多组学在衰老和神经退行性疾病中的应用

Jensen, Tanner D; Le Guen, Yann; Talozzi, Lia; Yang, Sherry; Gorzynski, John; Peña-Tauber, Andrés; Stewart, Ilaria; Ferrasse, Alexis; Nachun, Daniel; Arriaga, Maggie T; Lee, Justin; Pulgrossi, Rafael Catoia; Park, Junyoung; Zhang, Jingyu; Wagner, Anthony D; Mormino, Elizabeth C; Poston, Kathleen L; Henderson, Victor W; He, Zihuai; Wyss-Coray, Tony; Montgomery, Stephen B; Ashley, Euan A; Greicius, Michael D

APOE loss-of-function variants: Compatible with longevity and associated with resistance to Alzheimer's disease pathology

APOE功能缺失变异体:与长寿相容,并与对阿尔茨海默病病理的抵抗力相关

Augustine Chemparathy,Yann Le Guen,Sunny Chen,Eun-Gyung Lee,Lesley Leong,John E Gorzynski,Tanner D Jensen,Alexis Ferrasse,Guangxue Xu,Hong Xiang,Michael E Belloy,Nandita Kasireddy,Andrés Peña-Tauber,Kennedy Williams,Ilaria Stewart,Lia Talozzi,Thomas S Wingo,James J Lah,Suman Jayadev,Chadwick M Hales,Elaine Peskind,Daniel D Child,Sigrun Roeber,C Dirk Keene,Le Cong,Euan A Ashley,Chang-En Yu,Michael D Greicius

A 3'UTR Insertion Is a Candidate Causal Variant at the TMEM106B Locus Associated With Increased Risk for FTLD-TDP

TMEM106B基因座上的3'UTR插入是与FTLD-TDP风险增加相关的候选致病变异。

Chemparathy, Augustine; Le Guen, Yann; Zeng, Yi; Gorzynski, John; Jensen, Tanner D; Yang, Chengran; Kasireddy, Nandita; Talozzi, Lia; Belloy, Michael; Stewart, Ilaria; Gitler, Aaron D; Wagner, Anthony D; Mormino, Elizabeth; Henderson, Victor W; Wyss-Coray, Tony; Ashley, Euan; Cruchaga, Carlos; Greicius, Michael D

Understanding the Phage-Host Interaction Mechanism toward Improving the Efficacy of Current Antibiotics in Mycobacterium abscessus

了解噬菌体-宿主相互作用机制以提高当前抗生素对脓肿分枝杆菌的疗效

Mylene Gorzynski, Katalla De Ville, Tiana Week, Tiana Jaramillo, Lia Danelishvili

A 3'UTR Insertion Is a Candidate Causal Variant at the TMEM106B Locus Associated with Increased Risk for FTLD-TDP

TMEM106B基因座上的3'UTR插入是与FTLD-TDP风险增加相关的候选致病变异。

Chemparathy, Augustine; Guen, Yann Le; Zeng, Yi; Gorzynski, John; Jensen, Tanner; Yang, Chengran; Kasireddy, Nandita; Talozzi, Lia; Belloy, Michael E; Stewart, Ilaria; Gitler, Aaron D; Wagner, Anthony D; Mormino, Elizabeth; Henderson, Victor W; Wyss-Coray, Tony; Ashley, Euan; Cruchaga, Carlos; Greicius, Michael D