Discovery of GLPG2737, a Potent Type 2 Corrector of CFTR for the Treatment of Cystic Fibrosis in Combination with a Potentiator and a Type 1 Co-corrector
GLPG2737 的发现，是一种强效的 CFTR 2 型校正剂，可与增强剂和 1 型辅助校正剂联合用于治疗囊性纤维化。
期刊:Journal of Medicinal Chemistry
影响因子:6.8
doi:10.1021/acs.jmedchem.3c01790
Pizzonero, Mathieu; Akkari, Rhalid; Bock, Xavier; Gosmini, Romain; De Lemos, Elsa; Duthion, Béranger; Newsome, Gregory; Mai, Thi-Thu-Trang; Roques, Virginie; Jary, Hélène; Lefrancois, Jean-Michel; Cherel, Laetitia; Quenehen, Vanessa; Babel, Marielle; Merayo, Nuria; Bienvenu, Natacha; Mammoliti, Oscar; Coti, Ghjuvanni; Palisse, Adeline; Cowart, Marlon; Shrestha, Anurupa; Greszler, Stephen; Van Der Plas, Steven; Jansen, Koen; Claes, Pieter; Jans, Mia; Gees, Maarten; Borgonovi, Monica; De Wilde, Gert; Conrath, Katja
