日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Safety and preliminary immunogenicity of JNJ-64041809, a live-attenuated, double-deleted Listeria monocytogenes-based immunotherapy, in metastatic castration-resistant prostate cancer

JNJ-64041809（一种基于减毒活双缺失单核细胞增生李斯特菌的免疫疗法）在转移性去势抵抗性前列腺癌中的安全性和初步免疫原性

期刊:Prostate Cancer and Prostatic Diseases
影响因子:5.8
doi:10.1038/s41391-021-00402-8
Drake, Charles G; Pachynski, Russell K; Subudhi, Sumit K; McNeel, Douglas G; Antonarakis, Emmanuel S; Bauer, Todd M; Lauer, Peter; Brockstedt, Dirk; Patricia, Daniel; Wade, Mark; Zudaire, Enrique; Bandyopadhyay, Nibedita; Parasrampuria, Dolly A; Girgis, Suzette; Mason, Gary E; Knoblauch, Roland E; Stone, Nicole; Infante, Jeffrey R; Gottardis, Marco M; Fong, Lawrence
肿瘤
肿瘤免疫
单核细胞
细胞生物学
前列腺癌
免疫/内分泌
发表日期：2022
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Discovery of the Selective CYP17A1 Lyase Inhibitor BMS-351 for the Treatment of Prostate Cancer

发现选择性CYP17A1裂解酶抑制剂BMS-351用于治疗前列腺癌

期刊:ACS Medicinal Chemistry Letters
影响因子:4
doi:10.1021/acsmedchemlett.5b00310
Huang, Audris; Jayaraman, Lata; Fura, Aberra; Vite, Gregory D; Trainor, George L; Gottardis, Marco M; Spires, Thomas E; Spires, Vanessa M; Rizzo, Cheryl A; Obermeier, Mary T; Elzinga, Paul A; Todderud, Gordon; Fan, Yi; Newitt, John A; Beyer, Sophie M; Zhu, Yongxin; Warrack, Bethanne M; Goodenough, Angela K; Tebben, Andrew J; Doweyko, Arthur M; Gold, David L; Balog, Aaron
肿瘤
肿瘤免疫
多发性硬化症
CYP17A1
前列腺癌
351
发表日期：2016
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IGFBP ratio confers resistance to IGF targeting and correlates with increased invasion and poor outcome in breast tumors.

IGFBP 比率赋予乳腺肿瘤对 IGF 靶向治疗的抵抗力，并与乳腺肿瘤侵袭性增强和预后不良相关

期刊:Clinical Cancer Research
影响因子:10.2
doi:10.1158/1078-0432.CCR-11-1806
Becker Marc A, Hou Xiaonan, Harrington Sean C, Weroha S John, Gonzalez Sergio E, Jacob Kristina A, Carboni Joan M, Gottardis Marco M, Haluska Paul
肿瘤
肿瘤免疫
发表日期：2012
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Drug efflux by breast cancer resistance protein is a mechanism of resistance to the benzimidazole insulin-like growth factor receptor/insulin receptor inhibitor, BMS-536924

乳腺癌耐药蛋白介导的药物外排是苯并咪唑类胰岛素样生长因子受体/胰岛素受体抑制剂BMS-536924产生耐药性的机制之一。

期刊:Molecular Cancer Therapeutics
影响因子:5.5
doi:10.1158/1535-7163.MCT-10-0438
Hou, Xiaonan; Huang, Fei; Carboni, Joan M; Flatten, Karen; Asmann, Yan W; Ten Eyck, Cynthia; Nakanishi, Takeo; Tibodeau, Jennifer D; Ross, Douglas D; Gottardis, Marco M; Erlichman, Charles; Kaufmann, Scott H; Haluska, Paul
肿瘤
肿瘤免疫
信号转导
多发性硬化症
乳腺癌
免疫/内分泌
发表日期：2011
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HER receptor signaling confers resistance to the insulin-like growth factor-I receptor inhibitor, BMS-536924

HER受体信号传导赋予了对胰岛素样生长因子-I受体抑制剂BMS-536924的耐药性

期刊:Molecular Cancer Therapeutics
影响因子:5.5
doi:10.1158/1535-7163.MCT-08-0493
Haluska, Paul; Carboni, Joan M; TenEyck, Cynthia; Attar, Ricardo M; Hou, Xiaonan; Yu, Chunrong; Sagar, Malvika; Wong, Tai W; Gottardis, Marco M; Erlichman, Charles
信号转导
多发性硬化症
免疫/内分泌
发表日期：2008
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The androgen receptor can signal through Wnt/beta-Catenin in prostate cancer cells as an adaptation mechanism to castration levels of androgens

雄激素受体可通过 Wnt/β-catenin 信号通路在前列腺癌细胞中发出信号，以此作为对去势水平雄激素的一种适应机制。

期刊:BMC Cell Biology
影响因子:
doi:10.1186/1471-2121-9-4
Schweizer, Liang; Rizzo, Cheryl A; Spires, Thomas E; Platero, J Suso; Wu, Qiuyan; Lin, Tai-An; Gottardis, Marco M; Attar, Ricardo M
肿瘤
肿瘤免疫
信号转导
Wnt/β-Catenin
细胞生物学
前列腺癌
免疫/内分泌
发表日期：2008
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