日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Bispecific antibodies against the hepatitis C virus E1E2 envelope glycoprotein

针对丙型肝炎病毒E1E2包膜糖蛋白的双特异性抗体

Radić, Laura; Offersgaard, Anna; Kadavá, Tereza; Zon, Ian; Capella-Pujol, Joan; Mulder, Fabian; Koekkoek, Sylvie; Spek, Vera; Chumbe, Ana; Bukh, Jens; van Gils, Marit J; Sanders, Rogier W; Yin, Victor C; Heck, Albert J R; Gottwein, Judith M; Sliepen, Kwinten; Schinkel, Janke

SARS-CoV-2 Mpro inhibitor ensitrelvir: asymmetrical cross-resistance with nirmatrelvir and emerging resistance hotspots

SARS-CoV-2 Mpro抑制剂恩西替利韦:与尼尔马替利韦存在不对称交叉耐药性及耐药性热点地区出现

Zhou, Yuyong; Gammeltoft, Karen A; Tjørnelund-Sjursen, Helena D; Ryberg, Line A; Offersgaard, Anna; Czarnota, Anna; Duan, Zhe; Pham, Long V; Fahnøe, Ulrik; Peters, Günther H J; Ramirez, Santseharay; Bukh, Jens; Gottwein, Judith M

Identification of novel neutralizing determinants for protection against HCV

鉴定新型中和决定簇以预防丙型肝炎病毒感染

Alzua, Garazi P; Pihl, Anne F; Offersgaard, Anna; Velázquez-Moctezuma, Rodrigo; Duarte Hernandez, Carlos R; Augestad, Elias H; Fahnøe, Ulrik; Mathiesen, Christian K; Krarup, Henrik; Law, Mansun; Prentoe, Jannick; Bukh, Jens; Gottwein, Judith M

Versatile SARS-CoV-2 Reverse-Genetics Systems for the Study of Antiviral Resistance and Replication.

用于研究抗病毒耐药性和复制的多功能 SARS-CoV-2 反向遗传学系统

Fahnøe Ulrik, Pham Long V, Fernandez-Antunez Carlota, Costa Rui, Rivera-Rangel Lizandro René, Galli Andrea, Feng Shan, Mikkelsen Lotte S, Gottwein Judith M, Scheel Troels K H, Ramirez Santseharay, Bukh Jens

Antigenic and immunogenic evaluation of permutations of soluble hepatitis C virus envelope protein E2 and E1 antigens

可溶性丙型肝炎病毒包膜蛋白E2和E1抗原排列组合的抗原性和免疫原性评价

Prentoe, Jannick; Janitzek, Christoph M; Velázquez-Moctezuma, Rodrigo; Goksøyr, Louise; Olsen, Rebecca W; Fanalista, Margherita; Augestad, Elias H; Thrane, Susan; Pihl, Anne F; Gottwein, Judith M; Sander, Adam F; Bukh, Jens

High density Huh7.5 cell hollow fiber bioreactor culture for high-yield production of hepatitis C virus and studies of antivirals

高密度Huh7.5细胞中空纤维生物反应器培养用于高产丙型肝炎病毒及抗病毒药物研究

Pihl, Anne F; Offersgaard, Anna F; Mathiesen, Christian K; Prentoe, Jannick; Fahnøe, Ulrik; Krarup, Henrik; Bukh, Jens; Gottwein, Judith M

Efficient Hepatitis C Virus Genotype 1b Core-NS5A Recombinants Permit Efficacy Testing of Protease and NS5A Inhibitors

高效的丙型肝炎病毒1b型核心-NS5A重组体可用于蛋白酶和NS5A抑制剂的疗效测试

Pham, Long V; Ramirez, Santseharay; Carlsen, Thomas H R; Li, Yi-Ping; Gottwein, Judith M; Bukh, Jens

Hepatitis C Virus Genotype 1 to 6 Protease Inhibitor Escape Variants: In Vitro Selection, Fitness, and Resistance Patterns in the Context of the Infectious Viral Life Cycle

丙型肝炎病毒基因型1至6蛋白酶抑制剂逃逸变异株:体外选择、适应性和耐药模式及其在病毒感染生命周期中的作用

Serre, Stéphanie B N; Jensen, Sanne B; Ghanem, Lubna; Humes, Daryl G; Ramirez, Santseharay; Li, Yi-Ping; Krarup, Henrik; Bukh, Jens; Gottwein, Judith M

Substitutions at NS3 Residue 155, 156, or 168 of Hepatitis C Virus Genotypes 2 to 6 Induce Complex Patterns of Protease Inhibitor Resistance

丙型肝炎病毒2至6型基因型NS3蛋白155、156或168位氨基酸残基的替换可诱导复杂的蛋白酶抑制剂耐药模式。

Jensen, Sanne B; Serre, Stéphanie B N; Humes, Daryl G; Ramirez, Santseharay; Li, Yi-Ping; Bukh, Jens; Gottwein, Judith M

Adaptive Mutations Enhance Assembly and Cell-to-Cell Transmission of a High-Titer Hepatitis C Virus Genotype 5a Core-NS2 JFH1-Based Recombinant

适应性突变增强了高滴度丙型肝炎病毒基因型5a核心-NS2 JFH1重组体的组装和细胞间传播

Mathiesen, Christian K; Prentoe, Jannick; Meredith, Luke W; Jensen, Tanja B; Krarup, Henrik; McKeating, Jane A; Gottwein, Judith M; Bukh, Jens