日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Myofibroblast programming blocks differentiation of TLS-organizing fibroblastic reticular cells in pancreatic cancer.

肌成纤维细胞编程阻断胰腺癌中TLS组织成纤维网状细胞的分化。

期刊:Cancer Cell
影响因子:44.5
doi:10.1016/j.ccell.2026.03.004
Kirschstein Elijah, Harder Olivia, Krull Jordan, Sikorski Madison, Khanal Shrijan, Mack Morgan, Ware Carl F, Evans Elizabeth, Gough Michael J, Ma Qin, Chen Wei, Young Kristina H, Gunderson Andrew J
胰腺癌
细胞生物学
成纤维细胞
发表日期：2026
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CMS subtypes correlate with complete response in trial of neoadjuvant Galunisertib plus chemoradiation in rectal cancer

CMS亚型与新辅助Galunisertib联合放化疗治疗直肠癌的试验中完全缓解相关

期刊:Translational Oncology
影响因子:4.1
doi:10.1016/j.tranon.2026.102690
Rajamanickam, Venkatesh; Simons, Noah D; Rosales, Wesley; Kravchenko, Anton; Yamazaki, Tomoko; Bernard, Brady; Piening, Brian; Domingo, Enric; Maughan, Timothy; Alvarez-Jimenez, Charlems; Desilvio, Thomas; Viswanath, Satish; Whiteford, Mark; Hayman, Amanda; O'Brien, David; Kiely, Maria X; Ahmad, Rehan; Gough, Michael J; Crittenden, Marka R; Young, Kristina H
肿瘤
肠癌
肿瘤免疫
多发性硬化症
发表日期：2026
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Fluorescence tracking Treg movement identifies anti-CCR8 and radiation as a therapeutic combination.

荧光追踪 Treg 的运动表明抗 CCR8 和放射疗法是一种有效的联合治疗方案。

期刊:iScience
影响因子:4.1
doi:10.1016/j.isci.2025.114572
Friedman David J, Ramin Sina, Blair Tiffany, Kramer Gwen, Bambina Shelly, Alice Alejandro F, Baird Jason, Medler Terry, Young Kristina H, Crittenden Marka R, Gough Michael J
IF
CCR8
T细胞
Treg
发表日期：2026
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The responses of HNSCC patients to immunotherapy are shown by two novel co-expression patterns

头颈部鳞状细胞癌患者对免疫疗法的反应可通过两种新的共表达模式来体现。

期刊:npj Precision Oncology
影响因子:8
doi:10.1038/s41698-025-00983-w
Daher-Ghanem, Narmeen; Sharon, Shay; Tao, Derrick; Sun, Zhaoyu; Rosales, Wesley; Rajamanickam, Venkatesh; Meng, Ryan; Kaur, Lakhvir; Bernard, Brady; Piening, Brian; Couey, Marcus; Gough, Michael J; Kravchenko-Balasha, Nataly
细胞生物学
肿瘤
肿瘤免疫
免疫/内分泌
发表日期：2025
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Radiation therapy causes a STING and MyD88-independent upregulation of CD80 and CD86 in macrophages and monocytes that limits tumor control

放射疗法会导致巨噬细胞和单核细胞中CD80和CD86的表达上调，而这种上调不依赖于STING和MyD88，从而限制肿瘤控制。

期刊:Cancer Immunology Immunotherapy
影响因子:5.1
doi:10.1007/s00262-025-04272-0
Preet Kaur, Aanchal; Baird, Jason R; Alice, Alejandro F; Kramer, Gwen; Friedman, David; Moran, Eva; Crittenden, Marka; Gough, Michael J
巨噬细胞
肿瘤
T细胞
肿瘤免疫
巨噬细胞
STING
CD8
CD80
CD86
单核细胞
细胞生物学
免疫/内分泌
发表日期：2025
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TGFβ limits proximal CD8+ TCR signaling via PTPN22 following strong and moderate agonism

TGFβ 在强激动剂和中等激动剂作用后通过 PTPN22 限制近端 CD8+ TCR 信号传导

期刊:Journal of Immunology
影响因子:3.4
doi:10.1093/jimmun/vkaf216
Gunderson, Andrew J; Jordan, Kelley; Yamazaki, Tomoko; Raué, Hans-Peter; Kramer, Gwen; Fox, Nathaniel; Slifka, Mark K; Gough, Michael J; Crittenden, Marka R; Young, Kristina H
信号转导
T细胞
CD8
TGFβ
发表日期：2025
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Myeloid MyD88 restricts CD8(+) T cell response to radiation therapy in pancreatic cancer

髓系MyD88限制胰腺癌中CD8(+) T细胞对放射治疗的反应

期刊:Scientific Reports
影响因子:3.9
doi:10.1038/s41598-023-35834-w
Medler, Terry R; Blair, Tiffany C; Alice, Alejandro F; Dowdell, Alexa K; Piening, Brian D; Crittenden, Marka R; Gough, Michael J
胰腺癌
T细胞
T细胞
CD8
免疫/内分泌
肿瘤
细胞生物学
肿瘤免疫
发表日期：2023
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The immunogenic radiation and new players in immunotherapy and targeted therapy for head and neck cancer

免疫原性辐射以及头颈癌免疫疗法和靶向治疗领域的新进展

期刊:Frontiers in Oral Health
影响因子:3.1
doi:10.3389/froh.2023.1180869
Sharon, Shay; Daher-Ghanem, Narmeen; Zaid, Deema; Gough, Michael J; Kravchenko-Balasha, Nataly
肿瘤
免疫/内分泌
肿瘤免疫
头颈癌
发表日期：2023
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ICOS is upregulated on T cells following radiation and agonism combined with radiation results in enhanced tumor control.

放射治疗后，T细胞上的ICOS表达上调，激动剂与放射治疗相结合可增强肿瘤控制

期刊:Scientific Reports
影响因子:3.9
doi:10.1038/s41598-022-19256-8
Blair Tiffany, Baird Jason, Bambina Shelly, Kramer Gwen, Gostissa Monica, Harvey Christopher J, Gough Michael J, Crittenden Marka R
细胞生物学
肿瘤
T细胞
发表日期：2022
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Response to radiotherapy in pancreatic ductal adenocarcinoma is enhanced by inhibition of myeloid-derived suppressor cells using STAT3 anti-sense oligonucleotide

利用STAT3反义寡核苷酸抑制髓系来源的抑制细胞可增强胰腺导管腺癌对放射治疗的反应。

期刊:Cancer Immunology Immunotherapy
影响因子:5.1
doi:10.1007/s00262-020-02701-w
Oweida, Ayman J; Mueller, Adam C; Piper, Miles; Milner, Dallin; Van Court, Benjamin; Bhatia, Shilpa; Phan, Andy; Bickett, Thomas; Jordan, Kimberly; Proia, Theresa; Schulick, Richard; Messersmith, Wells A; Del Chiaro, Marco; Clambey, Eric; Gough, Michael J; Williams, Jason; Hansen, Kirk; Goodman, Karyn; Karam, Sana D
STAT3
JAK/STAT
肿瘤
细胞生物学
肿瘤免疫
发表日期：2021
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