日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Proteolytic processing induces a conformational switch required for antibacterial toxin delivery

蛋白水解加工会诱导构象转变,而这种转变是抗菌毒素递送所必需的。

Nicholas L Bartelli ,Victor J Passanisi ,Karolina Michalska ,Kiho Song ,Dinh Q Nhan ,Hongjun Zhou ,Bonnie J Cuthbert ,Lucy M Stols ,William H Eschenfeldt ,Nicholas G Wilson ,Jesse S Basra ,Ricardo Cortes ,Zainab Noorsher ,Youssef Gabraiel ,Isaac Poonen-Honig ,Elizabeth C Seacord ,Celia W Goulding ,David A Low ,Andrzej Joachimiak ,Frederick W Dahlquist ,Christopher S Hayes

A novel therapeutic antibody screening method using bacterial high-content imaging reveals functional antibody binding phenotypes of Escherichia coli ST131

一种利用细菌高内涵成像技术的新型治疗性抗体筛选方法揭示了大肠杆菌ST131的功能性抗体结合表型

Maes, Mailis; Dyson, Zoe A; Smith, Sarah E; Goulding, David A; Ludden, Catherine; Baker, Stephen; Kellam, Paul; Reece, Stephen T; Dougan, Gordon; Bartholdson Scott, Josefin

Role of sapA and yfgA in Susceptibility to Antibody-Mediated Complement-Dependent Killing and Virulence of Salmonella enterica Serovar Typhimurium

sapA 和 yfgA 在鼠伤寒沙门氏菌血清型对抗体介导的补体依赖性杀伤作用的敏感性和毒力中的作用

Ondari, Edna M; Heath, Jennifer N; Klemm, Elizabeth J; Langridge, Gemma; Barquist, Lars; Goulding, David A; Clare, Simon; Dougan, Gordon; Kingsley, Robert A; MacLennan, Calman A

Differential Killing of Salmonella enterica Serovar Typhi by Antibodies Targeting Vi and Lipopolysaccharide O:9 Antigen.

针对 Vi 和脂多糖 O:9 抗原的抗体对伤寒沙门氏菌血清型的差异性杀灭作用

Hart Peter J, O'Shaughnessy Colette M, Siggins Matthew K, Bobat Saeeda, Kingsley Robert A, Goulding David A, Crump John A, Reyburn Hugh, Micoli Francesca, Dougan Gordon, Cunningham Adam F, MacLennan Calman A

Troponin T is essential for sarcomere assembly in zebrafish skeletal muscle.

肌钙蛋白T是斑马鱼骨骼肌肌节组装所必需的

Ferrante Maria I, Kiff Rebecka M, Goulding David A, Stemple Derek L

Convergent extension movements and ciliary function are mediated by ofd1, a zebrafish orthologue of the human oral-facial-digital type 1 syndrome gene

趋同延伸运动和纤毛功能由ofd1介导,ofd1是人类口面指综合征1型基因的斑马鱼同源基因。

Ferrante, Maria I; Romio, Leila; Castro, Silvia; Collins, John E; Goulding, David A; Stemple, Derek L; Woolf, Adrian S; Wilson, Stephen W