日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

NEK7 phosphorylation of cortactin modulates the migratory capacity of cells expressing EML4-ALK V3.

NEK7 对 cortactin 的磷酸化调节表达 EML4-ALK V3 的细胞的迁移能力。

Richardson Emily L, Knebel Axel, Straatman Kees R, Gourlay Robert, Lamont Douglas, Hardy Tara, Turnbull Robert E, Robinson Susan W, O'Regan Laura, Bayliss Richard, Fry Andrew M

Phosphorylation enables progressive microtubule-associated protein proteolysis and functionalisation during neural development.

磷酸化作用能够促进神经发育过程中微管相关蛋白的逐步水解和功能化。

Yang Zedeng, Liczmanska Magda, Hogg Elizabeth K J, Wallace Iona, Zhou Houjiang, Gourlay Robert, Squires Iolo, Li Ziyi, Hao Ying, Brown Fiona, Toth Rachel, Macartney Thomas, Hastie C James, Qi Yu Andy, Gierlinski Marek, Bustos Francisco, Findlay Greg M

An ERK5-KLF2 signalling module regulates early embryonic gene expression and telomere rejuvenation in stem cells

ERK5-KLF2信号模块调控早期胚胎基因表达和干细胞端粒再生

Brown, Helen A; Williams, Charles A C; Zhou, Houjiang; Rios-Szwed, Diana; Fernandez-Alonso, Rosalia; Mansoor, Saria; McMulkin, Liam; Toth, Rachel; Gourlay, Robert; Peltier, Julien; Dieguez-Martinez, Nora; Trost, Matthias; Lizcano, Jose M; Stavridis, Marios P; Findlay, Greg M

Parkin is activated by PINK1-dependent phosphorylation of ubiquitin at Ser65

Parkin 的激活依赖于 PINK1 依赖的泛素 Ser65 位点的磷酸化。

Kazlauskaite, Agne; Kondapalli, Chandana; Gourlay, Robert; Campbell, David G; Ritorto, Maria Stella; Hofmann, Kay; Alessi, Dario R; Knebel, Axel; Trost, Matthias; Muqit, Miratul M K

Protein associated with SMAD1 (PAWS1/FAM83G) is a substrate for type I bone morphogenetic protein receptors and modulates bone morphogenetic protein signalling.

与 SMAD1 相关的蛋白质 (PAWS1/FAM83G) 是 I 型骨形态发生蛋白受体的底物,并调节骨形态发生蛋白信号传导

Vogt Janis, Dingwell Kevin S, Herhaus Lina, Gourlay Robert, Macartney Thomas, Campbell David, Smith James C, Sapkota Gopal P

PINK1 is activated by mitochondrial membrane potential depolarization and stimulates Parkin E3 ligase activity by phosphorylating Serine 65

PINK1 由线粒体膜电位去极化激活,并通过磷酸化丝氨酸 65 位点刺激 Parkin E3 连接酶活性。

Kondapalli, Chandana; Kazlauskaite, Agne; Zhang, Ning; Woodroof, Helen I; Campbell, David G; Gourlay, Robert; Burchell, Lynn; Walden, Helen; Macartney, Thomas J; Deak, Maria; Knebel, Axel; Alessi, Dario R; Muqit, Miratul M K

The role of TBK1 and IKKε in the expression and activation of Pellino 1

TBK1 和 IKKε 在 Pellino 1 的表达和激活中的作用

Smith, Hilary; Liu, Xin-Yu; Dai, Liang; Goh, Eddy T H; Chan, Aye-Thu; Xi, Jiajia; Seh, Cheah-Chen; Qureshi, Insaf A; Lescar, Julien; Ruedl, Christiane; Gourlay, Robert; Morton, Simon; Hough, Joanne; McIver, Edward G; Cohen, Philip; Cheung, Peter C F

Polyubiquitin binding to optineurin is required for optimal activation of TANK-binding kinase 1 and production of interferon β.

多聚泛素与 optineurin 结合是 TANK 结合激酶 1 的最佳激活和干扰素 β 产生的必要条件

Gleason Catherine E, Ordureau Alban, Gourlay Robert, Arthur J Simon C, Cohen Philip