日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Kappa opioid receptor antagonism restores phosphorylation, trafficking and behavior induced by a disease-associated dopamine transporter variant

κ阿片受体拮抗剂可恢复由疾病相关的多巴胺转运体变体诱导的磷酸化、转运和行为。

Mayer, Felix P; Stewart, Adele; Varman, Durairaj Ragu; Moritz, Amy E; Foster, James D; Owens, Anthony W; Areal, Lorena B; Gowrishankar, Raajaram; Velez, Michelle; Wickham, Kyria; Phelps, Hannah; Katamish, Rania; Rabil, Maximilian; Jayanthi, Lankupalle D; Vaughan, Roxanne A; Daws, Lynette C; Blakely, Randy D; Ramamoorthy, Sammanda

Behaviorally penetrant, anomalous dopamine efflux exposes sex and circuit dependent regulation of dopamine transporters

行为学上可观察到的异常多巴胺外流揭示了多巴胺转运体的性别和回路依赖性调节

Stewart, Adele; Mayer, Felix P; Gowrishankar, Raajaram; Davis, Gwynne L; Areal, Lorena B; Gresch, Paul J; Katamish, Rania M; Peart, Rodeania; Stilley, Samantha E; Spiess, Keeley; Rabil, Maximilian J; Diljohn, Faakhira A; Wiggins, Angelica E; Vaughan, Roxanne A; Hahn, Maureen K; Blakely, Randy D

Kappa-opioid receptor activation reinstates nicotine self-administration in mice

κ-阿片受体激活可恢复小鼠的尼古丁自我给药行为

Gowrishankar, Raajaram; Gomez, Adrian; Waliki, Marie; Bruchas, Michael R

Defining circuit-specific roles for G protein-coupled receptors in aversive learning

明确G蛋白偶联受体在厌恶学习中的回路特异性作用

Gowrishankar, Raajaram; Bruchas, Michael R

Functional coding variation in the presynaptic dopamine transporter associated with neuropsychiatric disorders drives enhanced motivation and context-dependent impulsivity in mice

与神经精神疾病相关的突触前多巴胺转运蛋白的功能编码变异会增强小鼠的动机和情境依赖性冲动。

Davis, Gwynne L; Stewart, Adele; Stanwood, Gregg D; Gowrishankar, Raajaram; Hahn, Maureen K; Blakely, Randy D

The rare DAT coding variant Val559 perturbs DA neuron function, changes behavior, and alters in vivo responses to psychostimulants

罕见的DAT编码变异体Val559会扰乱多巴胺能神经元功能,改变行为,并改变体内对精神兴奋剂的反应。

Mergy, Marc A; Gowrishankar, Raajaram; Gresch, Paul J; Gantz, Stephanie C; Williams, John; Davis, Gwynne L; Wheeler, C Austin; Stanwood, Gregg D; Hahn, Maureen K; Blakely, Randy D

Antipsychotic drug-like effects of the selective M4 muscarinic acetylcholine receptor positive allosteric modulator VU0152100.

选择性 M4 毒蕈碱乙酰胆碱受体正变构调节剂 VU0152100 的抗精神病药物样作用

Byun Nellie E, Grannan Michael, Bubser Michael, Barry Robert L, Thompson Analisa, Rosanelli John, Gowrishankar Raajaram, Kelm Nathaniel D, Damon Stephen, Bridges Thomas M, Melancon Bruce J, Tarr James C, Brogan John T, Avison Malcolm J, Deutch Ariel Y, Wess Jürgen, Wood Michael R, Lindsley Craig W, Gore John C, Conn P Jeffrey, Jones Carrie K

Genetic targeting of the amphetamine and methylphenidate-sensitive dopamine transporter: on the path to an animal model of attention-deficit hyperactivity disorder

针对苯丙胺和哌甲酯敏感的多巴胺转运蛋白的基因靶向:构建注意力缺陷多动障碍动物模型的途径

Mergy, Marc A; Gowrishankar, Raajaram; Davis, Gwynne L; Jessen, Tammy N; Wright, Jane; Stanwood, Gregg D; Hahn, Maureen K; Blakely, Randy D

Phylogenetic comparison of exonic US4, US7 and UL44 regions of clinical herpes simplex virus type 1 isolates showed lack of association between their anatomic sites of infection and genotypic/sub genotypic classification

对临床分离的1型单纯疱疹病毒外显子US4、US7和UL44区域的系统发育比较显示,其感染部位与基因型/亚基因型分类之间缺乏关联。

Harishankar, Anusha; Jambulingam, Malathi; Gowrishankar, Raajaram; Venkatachalam, Annapoorni; Vetrivel, Umashankar; Ravichandran, Sathyabaarathi; Yesupadam, Samson Moses; Madhavan, Hajib Narahari Rao